Exploring Co-occurrence patterns and microbial diversity in the lung microbiome of patients with non-small cell lung cancer

Table 1 Characteristics of included studies

Datasets	Accession	16S HV region	Sequencing platform	Case (No.)	Control (No.)	Age (YO.)	References
1	PRJNA624822	*	*	245	231	40–90	[13]
2	PRJNA303190	V3–V4	Illumina MiSeq	50	207	40–80	[4]
3	PRJNA327258	NA	Illumina MiSeq	27	26	40–80	**
4	PRJNA647170	V3–V4	Illumina MiSeq	25	24	52–72	[14]
				347	488

Case: lung tumor tissues, Control: tumor-adjacent normal tissues, NA: Not Available, * Five regions of the 16S rRNA gene were amplified and sequenced on Illumina HiSeq, MiSeq, or NextSeq. ** Dataset 2 (published) and Dataset 3 (unpublished) were separately available in SRA. With further assessment, we noticed both datasets had been taken from the same population. Therefore, we omitted the repeated samples and considered these two separate studies

ISSN: 1471-2180