Table 1 Technical information of the four incorporated studies
From: Meta-analysis of the effects of proton pump inhibitors on the human gut microbiota
Reference | Country code | Design | No. of cases | No. of controls | Medication | DNA extraction | 16S Region | Sequencing platform |
|---|---|---|---|---|---|---|---|---|
Horvath et al. | Austria 1 | Case–control | 62 | 64 | NA | MagNA Pure LCDNA Isolation Kit | v1–v2 | MiSeq |
Castellani et al. | Austria 2 | Self-control | 12 | / | 8 weeks | PSP-Spin Stool DNA Kit | v1–v2 | MiSeq |
Lin et al. | China | Case–control | 58 | 60 | At least 1 month | QIAamp DNA Stool Mini Kit | v3–v4 | MiSeq |
Freedberg et al. | USA | Self-control | 12 | / | 8Â weeks | PowerFecal DNA Isolation Kit | v4 | MiSeq |