Genetic determinants of Biofilm formation of Helicobacter pylori using whole-genome sequencing

BMC Microbiology

Table 1 The significant variants associated with biofilm formation

Gene	SNP	Proportion in Low Biofilm	Proportion in High Biofilm	Naïve	FDR	Reference
Gene	SNP	Proportion in Low Biofilm	Proportion in High Biofilm	P-value	FDR	Reference
alpA	G196N	0.16	0.45	0.045	0.045	[11]
alpB	A223V	0.31	0.73	0.017	0.045	[11]
	G160S	0.38	0.91	0.002	0.036
	N156K	0.09	0.45	0.01	0.045
amiA	T168V	0.07	0.36	0.022	0.045	[21]
cagE	S419C	0.42	0.87	0.045	0.045	[15]
cgt	V34A	0.178	0.54	0.02	0.045	[22]
csd5	M125I	0.15	0.56	0.017	0.045	[21]
	P43S	0.1	0.44	0.026	0.045
	V110A	0.07	0.44	0.015	0.045
futB	E98fs	0.16	0.5	0.033	0.045	[15]
gluP	T85S	0.27	0.64	0.032	0.045	[23]
homD	A570T	0.09	0.36	0.04	0.045	[15]
	V249fs	0.13	0.45	0.029	0.045
murF	V250I	0.33	0	0.026	0.045	[21]
Gene	SNP	Proportion in Low Biofilm	Proportion in High Biofilm	P-value	FDR	Reference
alpB	T127A	0.911	0.636	0.04	0.045	[11]
csd4	C12Y	0.711	0.364	0.041	0.045	[21]
futB	L317I	0.432	0	0.01	0.045	[15]

ISSN: 1471-2180