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Table 2 Fractional inhibitory concentration (FIC) of antibiotics and vitamin C

From: Antibacterial effect of vitamin C against uropathogenic E. coli in vitro and in vivo

Antibiotic + vitamin C

(A + B)

FICA

FICB

FICI

Result

Meropenem + Vitamin C

0.125

0.25

0.375

Synergism

Levofloxacin + Vitamin C

0.125

0.25

0.375

Synergism

Ceftazidime + VItamin C

0.25

0.25

0.5

Synergism

Nitrofurantoin + Vitamin C

0.25

0.25

0.5

Synergism

Amp/Sulbactam + Vitamin C

0.5

0.25

0.75

Indifference

Cefazolin + Vitamin C

1

0.25

1.25

Indifference

Cefoxitin + Vitamin C

1

0.25

1.25

Indifference

  1. FICA FIC of antibiotic, FIC B FIC of vitamin C, FICI FIC index, The FIC index value ≤ 0.5 indicates synergy, > 0.5–4 indifference, and > 4 antagonism
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BMC Microbiology

ISSN: 1471-2180

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