Fig. 4
 S. pseudintermedius induce a stronger Th2 immune response than S. aureus. Each mouse (n = 6 mice/group) was challenged with S. aureus or S. pseudintermedius (108 CFU) by subcutaneous injection. Subcutaneous skin abscesses of the infected mice were observed on day 2 after infection. (A) Abscess pictures. (B) Abscess area measured 2 d post-infection. (C) Bacterial loads in the skin lesion. (D) Levels of cytokines gene expression on skin lesions were determined by qRT-PCR. Statistical analysis is by unpaired two-tailed Student’s t-test and *P < 0.05, **P < 0.01, ***P < 0.001; ****P < 0.0001. Three independent experiments were performed for mouse skin abscess model and qRT-PCR experiments