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Fig. 2 | BMC Microbiology

Fig. 2

From: Improvement of vaginal probiotics Lactobacillus crispatus on intrauterine adhesion in mice model and in clinical practice

Fig. 2

The formation of intrauterine adhesions is closely related to the fibrosis TGF-β1/Smads pathway. (A) Expression of fibrosis-related proteins in uterine tissues of intrauterine adhesion mice. Effects of Lactobacillus crimp on (B) TGF-β1, (C) p-smad2 /Smad2, (D) p-Smad3/Smad3, (E) MMP-9 and (F) α-SMA proteins related to fibrosis in uterine tissues of mice with intrauterine adhesion. C group, Control group; M group, Mechanical injury was used to construct a model of intrauterine adhesion; L group was treated with L. crispatus for intrauterine adhesion mice. *P < 0.05; **P < 0.01; ***P < 0.001. Western blotting images were cropped to improve the conciseness of the data, and the original images with visible membrane edges can be found in Supplementary Material

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