Table 1 Clinical characteristics of patients infected with PB-resistant K. pneumoniae
Patient | Strain | Residence time | Age/sex | Department | Underlying conditions | ICU stay time | Prior antibiotic exposure | Source of infection | Treated antibiotics in 72Â h | Discharge status |
|---|---|---|---|---|---|---|---|---|---|---|
1 | KP25 | 2020.11.4–2020.12.20 | 65/Male | ICU | Multiple fractures, Severe pneumonia, Acute renal injury, Hypertension | 47 | SCF, LZD, TGC, TZP | Wound | TGC, TZP | Unhealed |
2 | KP14 | 2020.11.17–2020.12.4 | 57/Female | Recovery unit | Pneumonia, Rupture of intracranial aneurysm, Abnormal liver function | 8 | TZP | Respiratory tract | TZP | critically ill |
3 | KP17 | 2021.12.14–2021.2.20 | 70/Male | ICU | Severe pneumonia, Lung cancer surgery, Hypertension | 47 | TZP, MEM, PB, VA, CAZ | Respiratory tract | SCF | Improved |
4 | KP16 | 2021.1.5–2021.1.15 | 37/Male | Pancreato-biliary surgery unit | Acute severe pancreatitis | None | CDZ | Digestive tract | CDZ | Improved |
5 | KP18 | 2021.1.13–2021.3.15 | 38/Male | ICU, Neurosurgery unit | Pneumonia, Intracranial infection, Abnormal liver function | 71 | MEM, PB | Respiratory tract | MEM, TZP | critically ill |
6 | KP21 | 2021.2.18–2021.3.26 | 77/Female | ICU | Hepatocellular carcinoma, Pneumonia, Hepatitis B | 8 | LVX, CN, SCF | Liver | MEM | Unhealed |
7 | KP20 | 2021.3.8–2021.3.19 | 70/Male | ICU, Respiratory unit | Lymphoma, Severe pneumonia, Abnormal liver function, Type II diabetes | 14 | MEM, PB | Respiratory tract | MEM, PB | Unhealed |
8 | KP24 | 2021.3.25–2021.5.27 | 52/Male | Integrated traditional Chinese and western medicine unit | Brainstem hemorrhage, Pneumonia, Hypertension, Type II diabetes | None | PB, TGC | Urinary tract | TGC | Improved |