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Table 4 Univariate relationship of the SARS-CoV-2 infection using One-Step RT-qPCR assay and One-Step LAMP technique with demographic variables

From: Rapid, sensitive, and specific detection of SARS-CoV-2 in nasopharyngeal swab samples of suspected patients using a novel one-step loop-mediated isothermal amplification (one-step LAMP) technique

Variables

 

One-Step RT-qPCR

P-value

Odds Ratio

(CI %95)

One-Step LAMP

P-value

Odds Ratio

(CI %95)

Negative

Positive

Negative

Positive

n (%)

n (%)

n (%)

n (%)

Gender

Male

63 (47.7)

69 (52.3)

0.817

1.060

(0.648–1.735)

64 (48.5)

68 (51.5)

0.615

1.14

(0.69–1.85)

Female

60 (49.2)

62 (50.8)

63 (51.6)

59 (48.4)

Age category

≤ 18

18 (51.4)

17 (48.6)

0.68

0.92

1.16

(0.56–2.37)

1.06

(0.35–3.17)

18 (51.4)

17 (48.6)

0.85

0.92

1.07

(0.52–2.19)

1.06

(0.35–3.17)

19–64

95 (47.7)

104 (52.3)

99 (49.7)

100 (50.3)

≥ 65

10 (50.0)

10 (50.0)

10 (50.0)

10 (50.0)

Occupancy

Urban

47 (34.3)

90 (65.7)

0.001

3.550

(2.11–5.96)

48 (35.0)

89 (65.0)

0.001

3.85

(2.28–6.49)

Rural

76 (65.0)

41 (35.0)

79 (67.5)

38 (32.5)

Clinical symptoms

Fever

11 (47.8)

12 (52.2)

0.952

1.03

(0.43–2.42)

11 (47.8)

12 (52.5)

0.827

1.10

(0.46–2.59)

Fever & Chills

19 (35.2)

35 (64.8)

0.030

1.99

(1.07–3.72)

20 (37.0)

34 (63.0)

0.033

1.95

(1.05–3.63)

Muscle aches

30 (41.1)

43 (58.9)

0.139

1.51

(0.87–2.62)

31 (42.5)

42 (57.5)

0.128

1.53

(0.88–2.64)

Headache

31 (44.9)

38 (55.1)

0.496

1.21

(0.7–2.11)

23 (47.8)

36 (52.5)

0.672

1.12

(0.64–1.96)

Sore throat

25 (38.5)

40 (61.5)

0.064

1.72

(0.97–3.06)

25 (38.5)

40 (61.5)

0.032

1.87

(1.05–3.33)

Cough

20 (38.5)

32 (61.5)

0.109

1.67

(0.89–3.1)

21 (40.4)

31 (59.6)

0.122

1.63

(0.87–3.02)

Loss of smell & taste

6 (28.6)

15 (71.4)

0.065

2.52

(0.94–6.72)

6 (28.6)

15 (71.4)

0.047

2.70

(1.01–7.20)

Diarrhea & Vomiting

1 (20.0)

4 (80.0)

0.232

3.84

(0.42–34.86)

1 (20.0)

4 (80.0)

0.210

4.09

(0.45–37.17)

Shortness of breath

4 (14.8)

23 (85.2)

0.001

6.33

(2.12–18.9)

7 (25.9)

20 (74.1)

0.011

3.20

(1.30–7.87)

Other

14 (45.2)

17 (54.8)

0.698

1.16

(0.54–2.47)

14 (45.2)

17 (54.8)

0.566

1.24

(0.58–2.65)

Underlying health conditions (UHC)

Endocrine diseases

2 (18.2)

9 (81.8)

0.059

4.46

(0.95–21.08)

2 (18.2)

9 (81.8)

0.049

4.76

(1.00–22.52)

Liver diseases

1 (50.0)

1 (50.0)

0.964

0.94

(0.06–15.17)

1 (50.0)

1 (50.0)

0.99

1

(0.06–16.16)

Kidney diseases

1 (20.0)

4 (80.0)

0.232

3.84

(0.42–34.86)

1 (20.0)

4 (80.0)

0.21

4.09

(0.45–37.17)

Gastrointestinal diseases

1 (50.0)

1 (50.0)

0.964

0.94

(0.06–15.17)

1 (50.0)

1 (50.0)

1.000

1.00

(0.06–16.16)

Pulmonary diseases

0 (0.0)

4 (100)

0.232

3.84

(0.42–34.86)

0 (0.0)

4 (100.0)

0.21

4.09

(0.45–37.2)

Cardiovascular diseases

0 (0.0)

7 (100)

0.073

6.89

(0.84–56.82)

0 (0.0)

7 (100.0)

0.064

7.35

(0.89–60.63)

No UHC

117(51.5)

110 (48.5)

0.006

3.72

(1.45–9.56)

121 (53.3)

106 (46.7)

0.004

4

(1.55–10.27)