Fig. 5
SigB-dependent induced and downregulated proteins for ΔsigB and Δbc1009 mutants compared to wt cells at 30°C and their cluster of orthologous group (COG). A- log2 fold change in protein expression. Positive and negative fold change values indicate induced and downregulated proteins, respectively. Grey symbols: induced/downregulated proteins that are SigB (and Bc1009)- dependent, i.e., differentially expressed proteins in ΔsigB and Δbc1009 mutants compared to wt cells at 30 °C; the numbers indicate the top 30 induced proteins (positive x-axis) or top 20 downregulated proteins (negative x-axis), with details listed in Table 4. White symbols: induced/downregulated proteins at 30 °C that are either only SigB-dependent or Bc1009-dependent, i.e., differentially expressed proteins in ΔsigB or Δbc1009 mutants compared to wt cells at 30 °C (see details in Supplementary Table S5A). The threshold of the p-value for each protein was < 0.05. N = 4. B- cluster of orthologous group (COG) function for SigB (and Bc1009)-induced and downregulated proteins. The number on the x-axis indicates the number of induced/downregulated proteins in respective COG groups. The underlying transcriptome data supporting this figure are presented in Supplementary Table S5B