Fig. 5

Placental and technical control samples cluster by study origin, mode of delivery, and gestational age at delivery

A) Beta diversity between placental (open circles) and technical control samples (open triangles) from studies which sequenced the V4 hypervariable region of the 16S rRNA gene is visualized through principal coordinate analysis (PCoA) based on the Bray-Curtis dissimilarity index. B) Beta diversity of placental samples without technical control samples from each study. C) Placental samples from the same six studies were characterized by mode of delivery and gestational age at delivery. Weighted average positions of ASVs greater than 1% were plotted as grey diamonds and labelled with genus level classifications. Asterisks indicate ASV sequence genus level classifications which were assigned by NCBI BLAST with the highest percent identity in excess of 95%.