Antimicrobial activity of ceftobiprole and comparator agents when tested against gram-positive and -negative organisms collected across China (2016–2018)

Table 2 Activity of ceftobiprole and comparator antimicrobial agents when tested against Enterococcus isolated from China (mg/L)

Antimicrobial agents	MIC Range	MIC₅₀	MIC₉₀	R%	S%
*Enterococcus faecalis* (24)
Ceftobiprole	0.06 – > 32	0.5	1	–	–
Linezolid	0.5 – 4	0.5	2	0	91.7
Vancomycin	0.5 – 2	0.5	1	0	100
Ampicillin	1 – > 128	1	4	8.3	91.7
Ciprofloxacin	0.25 – > 32	1	> 32	29.2	70.8
Erythromycin	1 – > 128	> 128	> 128	62.5	0
*Enterococcus faecium* (23)
Ceftobiprole	0.5 – > 32	> 32	> 32	–	–
Linezolid	0.25 – 1	0.5	0.5	0	100
Vancomycin	0.25 – 4	0.5	0.5	0	100
Ampicillin	1 – > 128	> 128	> 128	82.6	17.4
Ciprofloxacin	1 – > 32	> 32	> 32	87	8.7
Erythromycin	0.125 – > 128	> 128	> 128	91.3	4.3

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