Insights on the performance of phenotypic tests versus genotypic tests for the detection of carbapenemase-producing Gram-negative bacilli in resource-limited settings

Table 2 Statistical association between carbapenemase enzyme and phenotypic tests with their respective p values

Pearson Chi-Square (two-tailed P value)
Carbapenamase enzyme	Phenotypic Tests	Enterobacterales	A. baumannii	P. aeruginosa	Non-glucose fermenting GNB	Total tested isolates
bla _KPC	MHT	P = 0.334	P = 0.126	P = 0.428	P = 0.116	P = 0.096
	mCIM	P = 0.525	P = 0.573	P = 0.715	P = 0.475	P = 0.500
	BCT	P = 0.084	P = 0.693	P = 0.188	P = 0.261	P = 0.088
	CDT	P = 0.192	P = 0.136	P = 0.071	P = 0.021*	P = 0.020*
bla _NDM	MHT	P = 0.053	P = 0.145	NA	P = 0.121	P = 0.009*
	mCIM	P = 0.159	P = 0.881	NA	P = 0.707	P = 0.684
	BCT	P = 0.631	P = 0.193	NA	P = 0.072	P = 0.464
	CDT	P = 0.017*	P = 0.100	NA	P = 0.052	P = 0.001*
bla _VIM	MHT	P = 0.039*	P = 0.005*	P = 0.014*	P = 0.006*	P = 0.000*
	mCIM	P = 0.056	P = 0.738	P = 0.273	P = 0.526	P = 0.350
	BCT	P = 0.732	P = 0.136	NA	P = 0.159	P = 0.943
	CDT	P = 0.033*	P = 0.001*	P = 0.030*	P = 0.004*	P = 0.000*
bla _GIM	MHT	P = 0.519	P = 0.727	P = 0.260	P = 0.738	P = 0.615
	mCIM	P = 0.309	P = 0.512	P = 0.657	P = 0.707	P = 0.523
	BCT	P = 0.041*	P = 0.603	NA	P = 0.613	P = 0.446
	CDT	P = 0.406	P = 0.188	P = 0.118	P = 0.052	P = 0.048*
bla _OXA−48	MHT	P = 0.717	P = 0.003*	P = 0.428	P = 0.061	P = 0.115
	mCIM	P = 0.269	P = 0.472	P = 0.715	P = 0.319	P = 0.099
	BCT	P = 0.140	P = 0.495	NA	P = 0.63	P = 0.305
	CDT	P = 0.313	P = 0.816	P = 0.071	P = 0.277	P = 0.287

* Statistically significant, MHT, modified Hodge test, mCIM, modified carbapenem inactivation method, CDT, combined disk test by EDTA ; BCT, blue-carba test. Non glucose fermenting bacilli included A. baumannii, P. aeruginosa and Stenotrophomonas maltophilia isolates. NA: not applicable

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