Fig. 7From: Metformin reverse minocycline to inhibit minocycline-resistant Acinetobacter baumannii by destroy the outer membrane and enhance membrane potential in vitroThe effect of metformin on the membrane potential and ROS production of A. baumannii A156. A, B Metformin causes dissipation of membrane potential and minocycline does not affect membrane potential. C, D Increased generation of ROS were detected only in high concentrations of metformin. Minocycline alone or plus metformin do not affect ROS level. Data are expressed as the mean ± SD of three replicates, *p ≤ 0.05; **p ≤ 0.01Back to article page