Table 2 MIC50 and MIC90 values of M. intracellulare and M. avium
From: In vitro assessment of 17 antimicrobial agents against clinical Mycobacterium avium complex isolates
Antimicrobial agent | M. intracellulare (n = 81) MIC (μg/mL) | M. avium (n = 13) MIC (μg/mL) | ||||
|---|---|---|---|---|---|---|
Range | 50% | 90% | Range | 50% | 90% | |
CLA |  ≤ 0.06 to > 64 | 4 | 8 | 1–16 | 4 | 16 |
RFB |  ≤ 0.25 to > 8 | 2 | 4 |  ≤ 0.25–4 | 1 | 4 |
EMB | 1 to > 16 | 4 |  > 16 | 4 to > 16 | 16 |  > 16 |
INH | 2 to > 8 |  > 8 |  > 8 | 2 to > 8 |  > 8 |  > 8 |
MXF |  ≤ 0.12 to > 8 | 4 | 8 | 0.5 to > 8 |  > 8 |  > 8 |
RIF |  ≤ 0.12 to > 8 | 8 |  > 8 | 4 to > 8 | 8 |  > 8 |
SXT |  ≤ 0.12/2.38 to > 8/152 | 4/76 |  > 8/152 | 2/38 to > 8/152 |  > 8/152 |  > 8/152 |
AMI |  ≤ 1 to > 64 | 8 | 16 | 2–32 | 4 | 16 |
LZD |  ≤ 1 to > 64 | 32 | 64 | 4–64 | 32 | 64 |
CIP |  ≤ 0.12 to > 16 | 16 |  > 16 | 1 to > 16 |  > 16 |  > 16 |
STR |  ≤ 0.5 to > 64 | 16 | 64 | 2–32 | 16 | 32 |
DOX | 2 to > 16 |  > 16 |  > 16 |  > 16 |  > 16 |  > 16 |
ETH | 2.5 to > 20 |  > 20 |  > 20 | 5 to > 20 |  > 20 |  > 20 |
TZD |  ≤ 0.5 to > 32 | 8 | 16 | 1 to > 32 | 8 | 32 |
CFZ |  ≤ 0.25 to > 8 | 2 | 8 | 1–8 | 2 | 4 |
BDQ | 0.015–0.12 | 0.06 | 0.12 | 0.03–0.12 | 0.06 | 0.12 |
CS | 8 to > 64 | 32 | 64 | 16–64 | 32 | 64 |