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Table 4 Assosiation between prognosis and threshold value of relative abundance (permyriad)

From: Gallbladder microbiota composition is associated with pancreaticobiliary and gallbladder cancer prognosis

1. Totall (n = 219, Death:69)

     
 

Threshold value

(n)

HR

Cl95

p

Enterococcus

≧2023

(106)

1.65

(1.02–2.68)

0.040

Eggerthella

≧1

(15)

2.22

(1.01–4.86)

0.043

Klebsiella

≧1442

(13)

2.21

(1.01–4.83)

0.043

Corynebacterium

≧47

(14)

2.36

(1.13–4.94)

0.019

Enhydrobacter

≧59

(11)

2.27

(1.04–4.96)

0.034

Hungatella

≧96

(9)

2.74

(1.10–6.83)

0.025

Paracoccus

≧3

(8)

2.50

(1.01–6.22)

0.041

Dermacoccus

≧6

(7)

3.14

(1.14–8.65)

0.020

Citrobacter

≧260

(7)

2.60

(1.04–6.49)

0.032

Lawsonella

≧18

(5)

3.48

(1.09–11.11)

0.026

Pseudoxanthomonas

≧1

(4)

7.41

(2.29–23.96)

<0.001

Streptococcus

≧14

(127)

0.60

(0.37–0.96)

0.031

Escherichia.Shigella

≧35

(114)

0.59

(0.37–0.95)

0.029

Veillonella

≧51

(55)

0.50

(0.26–0.96)

0.033

Dialister

≧1

(29)

0.35

(0.13–0.96)

0.032

2. Bile Duct lesion (n = 92, Death:18)

     
 

Threshold value

(n)

HR

Cl95

p

Enterococcus

≧581

(85)

1.13

(1.16–1.49)

0.049

Corynebacterium

≧14

(12)

3.32

(1.13–9.72)

0.041

Haemophilus

≧198

(6)

4.88

(1.35–17.63)

0.007

Lawsonella

≧1

(13)

4.42

(1.36–14.37)

0.007

Staphylococcus

≧9

(26)

2.81

(1.01–7.80)

0.040

Enhydrobacter

≧27

(8)

3.65

(1.02–13.10)

0.032

Bacteroides

≧897

(9)

3.88

(1.07–14.05)

0.026

Hungatella

≧96

(3)

5.42

(1.18–24.80)

0.017

Streptococcus

≧18

(52)

0.35

(0.12–1.01)

0.042

Fusobacterium

≧3

(46)

0.26

(0.07–0.92)

0.025

Veillonella

≧1

(40)

0.20

(0.04–0.87)

0.017

3. Pancreas lesion (n = 100, Death:43)

     
 

Threshold value

(n)

HR

Cl95

p

Klebsiella

≧15

(45)

1.82

(0.99–3.35)

0.049

Veillonella

≧334

(9)

2.87

(1.11–7.39)

0.022

Acinetobacter

≧85

(8)

2.88

(1.11–7.45)

0.024

Selenomonas

≧2

(5)

3.49

(1.06–11.52)

0.030

Paracoccus

≧3

(4)

4.04

(1.23–13.21)

0.013

Enterococcus

≧149

(105)

0.37

(0.14–0.95)

0.031

Staphylococcus

≧68

(22)

0.28

(0.10–0.79)

0.011

Bacteroides

≧477

(26)

0.37

(0.15–0.94)

0.030

Raoultella

≧210

(14)

0.12

(0.02–0.89)

0.013

Streptococcus

≧480

(8)

0.55

(0.46–0.66)

0.046