Fig. 1
From: LysX2 is a Mycobacterium tuberculosis membrane protein with an extracytoplasmic MprF-like domain
Sequence alignment of the catalytic domain of MtLysX and MtLysX2. Clustal Omega alignment of the MtLysX2 hydrophilic C-terminal region (355 amino acids) with the MtLysX homologous region involved in the Lys-PG biosynthesis. Amino acids shown to be required for the catalytic activity in SaMprF and conserved in MtLysX are boxed [8]. Asterisk: positions with a single and fully conserved residue; colon: positions with conservation between amino acid groups of strongly similar properties; period: positions with conservation between amino acid groups of similar properties