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Table 1 Types, groups, and prioritization of antimicrobials classified as critically important in human and veterinary medicine

From: Genetic and antimicrobial resistance profiles of non-O157 Shiga toxin-producing Escherichia coli from different sources in Egypt

Antimicrobial agents

Disk concentration

Antimicrobial class

Medical importance

Prioritization criterion

Amikacin

30 μg

Aminoglycosides

High priority critically important

P2 and P3

Amoxicillin/ clavulanic acid

30 μg

Penicillins

Highest priority critically important

P2 and P3

Ampicillin

10 μg

Penicillins

Highest priority critically important

P2 and P3

Cephradine

10 μg

Cephalosporins

Highly important

NA

Chloramphenicol

15 μg

Amphenicols

Highly important

NA

Clindamycin

20 μg

Lincosamides

Highly important

NA

Doxycycline

20 μg

Tetracyclines

Highly important

NA

Erythromycin

20 μg

Macrolides and ketolides

Highest priority critically important

P1, P2 and P3

Nalidixic acid

30 μg

Quinolones

Highest priority critically important

P1, P2 and P3

Norocillin

10 μg

Penicillins

High priority critically important

P2 and P3

Oxytetracyclin

20 μg

Tetracyclines

Highly important

NA

Penicillin G

10 μg

Penicillins

High priority critically important

P2 and P3

Streptomycin

5 μg

Aminoglycosides

High priority critically important

P2 and P3