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Fig. 1 | BMC Microbiology

Fig. 1

From: Regulation of virulence and β-lactamase gene expression in Staphylococcus aureus isolates: cooperation of two-component systems in bloodstream superbugs

Fig. 1

Differential expression of virulence and β-lactamase regulatory genes in BSI isolates of S. aureus. a: Heatmap of virulence and β-lactamase regulatory genes expression patterns in all 91 S. aureus. Red represents up-regulation and blue down-regulation relative to control. b: The expression levels of β-lactamase regulatory genes in MDR, XDR, and PDR strains, discriminated based on p-value and log2 (fold-change) at an α level of 0.05. c: The expression levels of β-lactamase regulatory genes in hemolysin producer, toxin producer, and non-virulent strains, discriminated based on p-value and log2 (fold-change) at an α level of 0.05. d The expression levels of virulence regulatory genes in MDR, XDR, and PDR strains, discriminated based on p-value and log2 (fold-change) at an α level of 0.05. e: The expression levels of virulence regulatory genes in hemolysin producer, toxin producer, and non-virulent strains, discriminated based on p-value and log2 (fold-change) at an α level of 0.05. Error bars standard errors: 0.05. Student’s t-test and Tow-Way ANOVA test were performed for testing differences between groups. *: p < 0.05, **: p < 0.001, ***: p < 0.0001

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