Table 2 The role of PMQR in 31 FQ-sensitive CRKP isolates
Number of isolates | Carrying PMQR (frequency) | Mutation in QRDRs | CIP MIC (μg/mL) |
|---|---|---|---|
8 | – | No substitution | ≤0.25 (8 isolates) |
23 | aac(6′)-Ib-cr (11); qnrS1 (9); qnrB1 (1); aac(6′)-Ib-cr, qnrS1 (11); aac(6′)-Ib-cr, qnrS1, qnrB4 (1) | No substitution | 0.5 (10 isolates) 1 (1 isolate) ≤0.25 (12 isolates) |