Lactic acid bacteria that activate immune gene expression in Caenorhabditis elegans can antagonise Campylobacter jejuni infection in nematodes, chickens and mice

Table 1 Statistical analysis of the protection effects of LAB stains on C. elegans infected by C. jejuni NCTC 11168^a

Groups^b	Survival (%)	DT50^c(day)	P	Groups^b	Survival (%)	DT50^c(day)	P
OP50/C. jejuni	20.16	6.83		ZX6/C. jejuni	26.03	7.27	0.21
OP50	55.78	14.90	< 0.01	PC-T7/C. jejuni	25.56	8.85	0.21
422/C. jejuni	15.09	6.06	0.92	JS-WX-9-1/C. jejuni	29.01	9.58	0.20
B/C. jejuni	18.02	7.38	0.88	N8/C. jejuni	28.67	8.09	0.18
G14/C. jejuni	20.01	7.31	0.87	11,657/C. jejuni	31.20	10.45	0.16
X14/C. jejuni	16.42	7.23	0.88	YM-1/C. jejuni	31.29	11.13	0.11
LSQ3/C. jejuni	19.03	7.06	0.87	676/C. jejuni	27.05	10.66	0.10
591/C. jejuni	20.66	8.03	0.73	JS-SZ-1-5/C. jejuni	32.08	11.84	0.07
H17/C. jejuni	20.32	6.79	0.58	NCFM/C. jejuni	36.89	12.49	< 0.01
LGG/C. jejuni	21.05	7.65	0.57	N34/C. jejuni	37.52	12.39	< 0.01
1101/C. jejuni	21.03	7.55	0.57	427/C. jejuni	38.02	13.06	< 0.01
N29/C. jejuni	23.79	9.05	0.56	X13/C. jejuni	38.78	13.04	< 0.01
408/C. jejuni	21.43	8.41	0.55	720/C. jejuni	39.11	12.21	< 0.01
H29M–8 M/C. jejuni	22.17	7.81	0.55	2009/C. jejuni	39.48	12.16	< 0.01
730/C. jejuni	21.89	6.91	0.53	H33M-1/C. jejuni	40.12	13.09	< 0.01
H9/C. jejuni	22.81	8.45	0.51	13 M2/C. jejuni	42.01	13.56	< 0.01
ZX7/C. jejuni	22.95	9.18	0.46	L103/C. jejuni	44.41	12.67	< 0.01
430/C. jejuni	24.09	9.79	0.42	G20/C. jejuni	45.15	13.96	< 0.01
675/C. jejuni	22.67	7.98	0.41	1132/C. jejuni	45.18	13.76	< 0.01
Z7/C. jejuni	22.14	7.46	0.29	H27-1 L/C. jejuni	45.81	14.90	< 0.01
Z6/C. jejuni	15.03	8.32	0.27	*13–7/C. jejuni***	47.09	14.01	< 0.01
rui/C. jejuni	25.81	10.46	0.26	*Z5/C. jejuni***	57.42	15.11	< 0.01
9–5/C. jejuni	29.58	9.21	0.25	*N9/C. jejuni***	43.28	13.70	< 0.01

^aSummary of two or more separate experiments. Survival of worms on the last day (day13) of the assays was estimated with the Kaplan-Meier survival analysis
^bOP50/C. jejuni: treatment with E. coli OP50 in the first 3 days and then with C.jejuni when C. elegans after L4 stage. OP50: treatment with E. coli OP50 during the whole experiment when C. elegans after L4 stage. LAB/ C. jejuni: treatment with LAB in the first 3 days and then with C.jejuni when C. elegans after L4 stage. The time of L4 stage nematodes before fed any thallus was considered 0 day
^cDT50, the time at which half of the worms were dead

ISSN: 1471-2180