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Fig. 3 | BMC Microbiology

Fig. 3

From: Proteomic response of Escherichia coli to a membrane lytic and iron chelating truncated Amaranthus tricolor defensin

Fig. 3

(a) Volcano plot visualizing global changes in E. coli proteome after treatment with Atr-DEF2(G39-C54). Fold change is defined as the average of treatment values divided by control values across four biological replicates. The two vertical black lines indicate log2 fold change values of 1 and − 1. The horizontal black line indicates an FDR-adjusted P-value of 0.05. In total, 1598 proteins were quantified. Upon treatment with Atr-DEF2(G39-C54) 51 proteins showed decreased abundance (blue) and 82 showed increased abundance (red). (B) Fold changes of proteins showing significantly altered abundance associated with modification of OM charge, Fe-S cluster assembly (GO:1990229), Fe-S cluster binding (GO:0051536), and siderophore synthesis (GO:0019290)/transportation

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