Table 5 Proteins identified in B. dentium ATCC 27678 by proteomic analysis

2-Oxocarboxylic acid metabolism

bde01210

12

2-Oxocarboxylic acid metabolism

bks01210

9

2-Oxocarboxylic acid metabolism

blf01210

5

2-Oxocarboxylic acid metabolism

blx01210

1

2-Oxocarboxylic acid metabolism

bln01210

1

ABC transporters

bde02010

26

ABC transporters

bks02010

6

ABC transporters

blf02010

4

Acarbose and validamycin biosynthesis

bks00525

1

Acarbose and validamycin biosynthesis

bde00525

1

Acarbose and validamycin biosynthesis

boa00525

1

Alanine, aspartate and glutamate metabolism

bde00250

9

Alanine, aspartate and glutamate metabolism

bks00250

4

Alanine, aspartate and glutamate metabolism

blf00250

4

Alanine, aspartate and glutamate metabolism

bln00250

3

Amino sugar and nucleotide sugar metabolism

bde00520

13

Amino sugar and nucleotide sugar metabolism

bks00520

9

Amino sugar and nucleotide sugar metabolism

blf00520

7

Amino sugar and nucleotide sugar metabolism

bln00520

2

Amino sugar and nucleotide sugar metabolism

boa00520

2

Aminoacyl-tRNA biosynthesis

bde00970

19

Aminoacyl-tRNA biosynthesis

bks00970

11

Aminoacyl-tRNA biosynthesis

blf00970

5

Aminoacyl-tRNA biosynthesis

bln00970

4

Aminoacyl-tRNA biosynthesis

boa00970

2

Arginine biosynthesis

bde00220

8

Arginine biosynthesis

bks00220

7

Arginine biosynthesis

blf00220

6

Arginine biosynthesis

bln00220

3

Bacterial secretion system

bde03070

6

Bacterial secretion system

bks03070

3

Bacterial secretion system

blf03070

2

Bacterial secretion system

bln03070

1

beta-Alanine metabolism

bde00410

1

beta-Lactam resistance

bde01501

3

beta-Lactam resistance

blf01501

1

Biosynthesis of amino acids

bde01230

38

Biosynthesis of amino acids

bks01230

23

Biosynthesis of amino acids

blf01230

18

Biosynthesis of amino acids

bln01230

7

Biosynthesis of amino acids

boa01230

4

Biosynthesis of amino acids

blx01230

1

Biosynthesis of antibiotics

bde01130

51

Biosynthesis of antibiotics

bks01130

31

Biosynthesis of antibiotics

blf01130

19

Biosynthesis of antibiotics

bln01130

9

Biosynthesis of antibiotics

boa01130

7

Biosynthesis of antibiotics

blx01130

2

Biosynthesis of antibiotics

blm01130

1

Biosynthesis of secondary metabolites

bde01110

62

Biosynthesis of secondary metabolites

bks01110

37

Biosynthesis of secondary metabolites

blf01110

24

Biosynthesis of secondary metabolites

bln01110

10

Biosynthesis of secondary metabolites

boa01110

8

Biosynthesis of secondary metabolites

blx01110

2

Biosynthesis of secondary metabolites

blm01110

1

Butanoate metabolism

bde00650

4

Butanoate metabolism

bks00650

2

Butanoate metabolism

blf00650

1

Butanoate metabolism

boa00650

1

C5-Branched dibasic acid metabolism

bde00660

4

C5-Branched dibasic acid metabolism

bks00660

3

Carbon metabolism

bde01200

25

Carbon metabolism

bks01200

15

Carbon metabolism

blf01200

10

Carbon metabolism

boa01200

5

Carbon metabolism

bln01200

3

Chloroalkane and chloroalkene degradation

bks00625

1

Chloroalkane and chloroalkene degradation

bde00625

1

Citrate cycle (TCA cycle)

bde00020

5

Citrate cycle (TCA cycle)

bks00020

2

Citrate cycle (TCA cycle)

boa00020

2

Citrate cycle (TCA cycle)

blf00020

1

Cyanoamino acid metabolism

bde00460

1

Cyanoamino acid metabolism

boa00460

1

Cysteine and methionine metabolism

bde00270

8

Cysteine and methionine metabolism

bks00270

6

Cysteine and methionine metabolism

blf00270

3

Cysteine and methionine metabolism

boa00270

2

Cysteine and methionine metabolism

blm00270

1

Degradation of aromatic compounds

bks01220

1

Degradation of aromatic compounds

bde01220

1

DNA replication

bde03030

2

DNA replication

bks03030

1

Fatty acid biosynthesis

boa00061

2

Fatty acid biosynthesis

bks00061

1

Fatty acid biosynthesis

blf00061

1

Fatty acid biosynthesis

bde00061

1

Fatty acid degradation

bks00071

1

Fatty acid degradation

bde00071

1

Fatty acid metabolism

boa01212

2

Fatty acid metabolism

bks01212

1

Fatty acid metabolism

blf01212

1

Fatty acid metabolism

bde01212

1

Fructose and mannose metabolism

bde00051

2

Fructose and mannose metabolism

bks00051

1

Fructose and mannose metabolism

boa00051

1

Galactose metabolism

bde00052

6

Galactose metabolism

bks00052

4

Galactose metabolism

blf00052

3

Galactose metabolism

boa00052

1

Glutathione metabolism

bde00480

3

Glutathione metabolism

bks00480

2

Glutathione metabolism

blf00480

1

Glycerolipid metabolism

bks00561

1

Glycerolipid metabolism

blf00561

1

Glycerolipid metabolism

bde00561

1

Glycerophospholipid metabolism

bde00564

4

Glycerophospholipid metabolism

bks00564

3

Glycerophospholipid metabolism

blf00564

2

Glycerophospholipid metabolism

bln00564

1

Glycine, serine and threonine metabolism

bde00260

9

Glycine, serine and threonine metabolism

bks00260

3

Glycine, serine and threonine metabolism

bln00260

1

Glycine, serine and threonine metabolism

blf00260

1

Glycine, serine and threonine metabolism

boa00260

1

Glycolysis / Gluconeogenesis

bde00010

11

Glycolysis / Gluconeogenesis

bks00010

10

Glycolysis / Gluconeogenesis

blf00010

5

Glycolysis / Gluconeogenesis

bln00010

3

Glycolysis / Gluconeogenesis

boa00010

3

Glycolysis / Gluconeogenesis

blm00010

1

Glyoxylate and dicarboxylate metabolism

bde00630

6

Glyoxylate and dicarboxylate metabolism

bks00630

2

Glyoxylate and dicarboxylate metabolism

blf00630

2

Histidine metabolism

blf00340

1

Histidine metabolism

bde00340

1

Homologous recombination

bde03440

2

Homologous recombination

bks03440

1

Inositol phosphate metabolism

boa00562

2

Inositol phosphate metabolism

bks00562

1

Inositol phosphate metabolism

bde00562

1

Lipopolysaccharide biosynthesis

boa00540

1

Lysine biosynthesis

bde00300

4

Lysine biosynthesis

bks00300

3

Metabolic pathways

bde01100

118

Metabolic pathways

bks01100

71

Metabolic pathways

blf01100

48

Metabolic pathways

boa01100

19

Metabolic pathways

bln01100

17

Metabolic pathways

blx01100

7

Metabolic pathways

blm01100

1

Methane metabolism

bde00680

7

Methane metabolism

bks00680

4

Methane metabolism

bln00680

2

Methane metabolism

blf00680

2

Methane metabolism

boa00680

1

Microbial metabolism in diverse environments

bde01120

36

Microbial metabolism in diverse environments

bks01120

24

Microbial metabolism in diverse environments

blf01120

13

Microbial metabolism in diverse environments

boa01120

6

Microbial metabolism in diverse environments

bln01120

3

Microbial metabolism in diverse environments

blm01120

1

Mismatch repair

bde03430

3

Mismatch repair

bks03430

2

Monobactam biosynthesis

bks00261

2

Monobactam biosynthesis

bde00261

2

Naphthalene degradation

bks00626

1

Naphthalene degradation

bde00626

1

Nicotinate and nicotinamide metabolism

blf00760

2

Nicotinate and nicotinamide metabolism

bks00760

2

Nicotinate and nicotinamide metabolism

bde00760

2

Nitrogen metabolism

bde00910

3

Nitrogen metabolism

bks00910

2

Nitrogen metabolism

blf00910

2

One carbon pool by folate

blf00670

2

One carbon pool by folate

bde00670

2

One carbon pool by folate

bks00670

1

Other glycan degradation

bde00511

1

Oxidative phosphorylation

bde00190

9

Oxidative phosphorylation

bks00190

6

Oxidative phosphorylation

blx00190

5

Oxidative phosphorylation

blf00190

4

Oxidative phosphorylation

bln00190

3

Oxidative phosphorylation

boa00190

2

Pantothenate and CoA biosynthesis

bde00770

6

Pantothenate and CoA biosynthesis

bks00770

4

Pantothenate and CoA biosynthesis

blf00770

3

Pantothenate and CoA biosynthesis

blx00770

1

Pantothenate and CoA biosynthesis

bln00770

1

Pantothenate and CoA biosynthesis

boa00770

1

Pentose and glucuronate interconversions

bde00040

4

Pentose and glucuronate interconversions

blf00040

1

Pentose and glucuronate interconversions

bks00040

1

Pentose phosphate pathway

bde00030

10

Pentose phosphate pathway

bks00030

6

Pentose phosphate pathway

blf00030

5

Peptidoglycan biosynthesis

bde00550

4

Peptidoglycan biosynthesis

bks00550

1

Peptidoglycan biosynthesis

blf00550

1

Phenylalanine, tyrosine and tryptophan biosynthesis

bde00400

2

Phenylalanine, tyrosine and tryptophan biosynthesis

blf00400

1

Phenylalanine, tyrosine and tryptophan biosynthesis

bks00400

1

Phosphotransferase system (PTS)

bks02060

1

Phosphotransferase system (PTS)

bde02060

1

Polyketide sugar unit biosynthesis

bks00523

1

Polyketide sugar unit biosynthesis

bde00523

1

Polyketide sugar unit biosynthesis

boa00523

1

Porphyrin and chlorophyll metabolism

bde00860

1

Propanoate metabolism

bde00640

7

Propanoate metabolism

bks00640

5

Propanoate metabolism

blf00640

3

Propanoate metabolism

blm00640

1

Protein export

bde03060

7

Protein export

bks03060

3

Protein export

blf03060

2

Protein export

bln03060

1

Purine metabolism

bde00230

19

Purine metabolism

bks00230

10

Purine metabolism

blf00230

6

Purine metabolism

bln00230

4

Purine metabolism

blx00230

2

Purine metabolism

boa00230

2

Pyrimidine metabolism

bde00240

11

Pyrimidine metabolism

bks00240

7

Pyrimidine metabolism

blf00240

5

Pyrimidine metabolism

bln00240

3

Pyrimidine metabolism

boa00240

2

Pyrimidine metabolism

blx00240

1

Pyruvate metabolism

bde00620

10

Pyruvate metabolism

bks00620

5

Pyruvate metabolism

boa00620

3

Pyruvate metabolism

blf00620

2

Pyruvate metabolism

blm00620

1

Quorum sensing

bde02024

17

Quorum sensing

bks02024

5

Quorum sensing

blf02024

4

Quorum sensing

bln02024

1

Riboflavin metabolism

boa00740

1

Ribosome

bde03010

47

Ribosome

bks03010

17

Ribosome

bln03010

15

Ribosome

blf03010

14

Ribosome

boa03010

10

Ribosome

blx03010

5

RNA degradation

bde03018

6

RNA degradation

bln03018

4

RNA degradation

bks03018

4

RNA degradation

blf03018

3

RNA degradation

boa03018

2

RNA degradation

bad03018

1

RNA polymerase

bde03020

4

RNA polymerase

bks03020

3

RNA polymerase

blf03020

2

RNA polymerase

blx03020

1

RNA polymerase

bln03020

1

Secondary bile acid biosynthesis

bks00121

1

Secondary bile acid biosynthesis

bde00121

1

Selenocompound metabolism

bde00450

2

Selenocompound metabolism

bks00450

1

Selenocompound metabolism

blf00450

1

Sphingolipid metabolism

bde00600

1

Starch and sucrose metabolism

bde00500

11

Starch and sucrose metabolism

bks00500

6

Starch and sucrose metabolism

blf00500

4

Starch and sucrose metabolism

boa00500

2

Starch and sucrose metabolism

bln00500

1

Streptomycin biosynthesis

bks00521

3

Streptomycin biosynthesis

bde00521

3

Streptomycin biosynthesis

boa00521

2

Streptomycin biosynthesis

blf00521

1

Taurine and hypotaurine metabolism

bde00430

3

Taurine and hypotaurine metabolism

bks00430

2

Taurine and hypotaurine metabolism

blf00430

1

Thiamine metabolism

bde00730

1

Two-component system

bde02020

4

Two-component system

blf02020

2

Two-component system

bks02020

1

Tyrosine metabolism

bks00350

1

Tyrosine metabolism

bde00350

1

Valine, leucine and isoleucine biosynthesis

bde00290

7

Valine, leucine and isoleucine biosynthesis

bks00290

4

Valine, leucine and isoleucine biosynthesis

blf00290

3

Valine, leucine and isoleucine biosynthesis

blx00290

1

Valine, leucine and isoleucine biosynthesis

bln00290

1

Valine, leucine and isoleucine degradation

bde00280

2

Valine, leucine and isoleucine degradation

bks00280

1

Valine, leucine and isoleucine degradation

blf00280

1

Vancomycin resistance

bde01502

1

Vitamin B6 metabolism

bde00750

1