Identification and functional analysis of the SARS-COV-2 nucleocapsid protein

BMC Microbiology

Table 4 The analysis of SARS-COV-2 N protein phosphorylation site multiple amino acid variant

Sites	Deletion			Insertion			Replacements
Sites	Variant	score	Prediction	Variant	score	Prediction	Variant	score	Prediction
49 T	T49_S51del	−4.946	D^a	T49_S51dup	−1.515	N	T49delinsSW	−3.009	D
232S	S232_M234del	−1.561	N	S232_M234dup	−1.573	N	S232delinsMS	−1.350	N
245 T	T245_T247del	−5.955	D	T245_T247dup	−3.081	D	T245delinsTK	−0.686	N
366 T	T366_P368del	−3.160	D	T366_P368dup	−0.983	N	T366delinsPK	−0.985	N
379 T	T379_A381del	−1.021	N	T379_A381dup	0.060	N	T379delinsAL	−1.584	N
391 T	T391_T393del	−0.007	N	T391_T393dup	−0.175	N	T391delinsTL	−1.299	N
393 T	T393_L395del	0.779	N	T393_L395dup	−1.736	N	T393delinsLP	−1.429	N
413S	S413_D415del	−1.187	N	S413_D415dup	1.058	N	S413delinsDS	1.891	N
417 T	T417_A419del	0.182	N	T417_A419dup	0.488	N	T417delinsAA	0.420	N

^aDefault threshold is − 2.5, that is: Variants with a score equal to or below − 2.5 are considered “Deleterious”; Variants with a score above − 2.5 are considered “Neutral”

ISSN: 1471-2180