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Table 2 Genes with functional annotation, with sites under positive selection pressure in recurrent but not in single infections. Pvalues are given for log-likelihood ratio test between M1a and M2a models with or without adjustment for multiple hypothesis testing. Adjusted p-values < 0.05 were considered significant

From: Higher genome variability within metabolism genes associates with recurrent Clostridium difficile infection

gene

pvalue-recurrent

pvalue-single

padjust-recurrent

padjust-single

tyrB

2.12E-05

9.97E-01

3.21E-04

1.00E+ 00

cdd3

6.02E-12

1.06E-01

1.63E-10

1.00E+ 00

fatC

1.10E-04

7.96E-01

1.45E-03

1.00E+ 00

opuCC

1.41E-03

6.55E-01

1.46E-02

1.00E+ 00

asnB

2.22E-07

8.77E-02

4.23E-06

1.00E+ 00

glsA

1.81E-07

9.70E-01

3.59E-06

1.00E+ 00

gltA

8.87E-05

9.96E-01

1.23E-03

1.00E+ 00

group_18063

1.90E-03

9.97E-01

1.77E-02

1.00E+ 00

selA

1.71E-03

5.32E-02

1.66E-02

1.00E+ 00

prdF

0.00E+ 00

9.60E-01

0.00E+ 00

1.00E+ 00

rapL

1.26E-07

8.07E-01

2.66E-06

1.00E+ 00

cheC

2.29E-03

7.83E-01

2.11E-02

1.00E+ 00

mtnN

1.89E-05

7.46E-01

2.95E-04

1.00E+ 00

accA

5.01E-03

6.96E-01

4.09E-02

1.00E+ 00

gph

2.73E-03

5.43E-01

2.43E-02

1.00E+ 00

hpt

3.15E-03

8.94E-01

2.70E-02

1.00E+ 00

hydE

1.06E-04

9.99E-01

1.44E-03

1.00E+ 00

actI

1.14E-03

9.16E-01

1.25E-02

1.00E+ 00

folC

0.00E+ 00

9.83E-01

0.00E+ 00

1.00E+ 00

xylA

4.29E-15

9.78E-01

1.30E-13

1.00E+ 00

csdA

1.63E-171

9.09E-01

1.05E-169

1.00E+ 00

dacF

1.62E-09

4.24E-02

3.89E-08

8.73E-01

tcdB

7.06E-20

1.31E-02

3.03E-18

3.98E-01

rnr

7.34E-16

8.11E-01

2.52E-14

1.00E+ 00

regB

2.47E-07

6.61E-03

4.54E-06

2.43E-01