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Table 5 Drug Susceptibility Profiles of patients with HIV Drug Resistance Mutations Detected

From: Low levels of HIV-1 drug resistance mutations in patients who achieved viral re-suppression without regimen switch: a retrospective study

Patient No.RegimenDrug Resistance Mutation TypesSusceptibility to 1 L DrugsSusceptibility to 2 L Drugs2 L GSSSubtype
NRTIsNNRTIsPIsABCAZTFTC3TCTDFEFVETRNVPRPVDRV/rATV/rLPV/r
1bOthers/FTC/NVPNoneV90IK20ISSaSSaSSSaSSSSS3.002_AG
2TDF/FTC/NVPNoneV90IVK20ISSaSSaSSSaSSSSS3.002_AG
3AZT/3TC/EFVNoneNoneM46 L, K20ISaSSaSSaSSSSSSS2.75G
4#Others/3TC/EFVNoneNoneL10I, L23ILSaSSaSS*SSSSSSS3.0A1
5AZT/3TC/NVPNoneE138EGNoneSaSSaSSSS*SLSSS3.0C
6TDF/FTC/EFVNoneK103Q, E138AEK20ISSaSSaSaSSSLSSS3.0G
7AZT/3TC/NVPNoneV90IV, V108IVNoneSaSSaSSSSaLSSSS3.0J
8AZT/3TC/NVPNoneV108IK20ISaSSaSSSSaLSSSS3.0G
9AZT/3TC/EFVNoneK103 NK20ISaSSaSSaHSHSSSS3.0G
10AZT/3TC/EFVNoneV106A, F227 LK20ISaSSaSSaHSHSSSS3.002_AG
11bOthers/FTC/NVPNoneK103KNK20ISSaSSaSHSaHSSSS3.002_AG
12TDF/FTC/NVPNoneV90I, K103 NK20ISSaSSaSHSaHSSSS3.002_AG
13AZT/3TC/NVPM184 VK103 N, E138AK20ILaSHaHSHSaHLSSS2.0G
14AZT/3TC/EFVD67DN, K70R, M184 V, K219EK103 N, V108IK20ILaLHaHLaHSHSSSS1.502_AG
15TDF/3TC/EFVK70E, M184 VK103 N, V108I, H221YL10I, K20ILSHaHaLaHSHSSSS2.002_AG
16AZT/3TC/NVPM184 VA98AG, K101E, Y181CK20ILaSHaHSLLaHHSSS2.002_AG
  1. S Susceptible and Potential low-level resistance, L Low-level resistance and Intermediate-level resistance, H High-level resistance. NRTIs Nucleoside Reverse Transcriptase Inhibitors, NNRTIs Non-Nucleoside Reverse Transcriptase Inhibitors, PIs Protease Inhibitors; 1 L-First-line; 2 L = Second-line: GSS Genotype Sensitivity Score. aIndicate drugs in patient’s First-line regimen; bOthers = Backbone NRTI was switched