Table 4 Antimicrobial profile and amino acid types in QRDRs and PMQRs analysis of S. dysentery with resistance to fluoroquinolones
Strain name | Antimicrobial profile | QRDRs | PMQR | ST | PT | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
gyrA | parC | aac(6′)-Ib-cr | qnr | qepA | |||||||
83 (S) | 87 (D) | 80 (S) | 83 (S) | ||||||||
SD020 | RT1 | ENR/KZ/CRO/CTX | L | D | I | L | + | – | – | 57 | 15 |
SD002 | RT2 | NOR/OFX/KZ/E/C/TE/S/CN | L | D | S | L | + | – | – | 229 | 6 |
SD026 | RT2 | NOR/OFX/KZ/E/C/TE/S/CN | L | D | S | L | + | – | – | 229 | 6 |
SD036 | RT2 | NOR/OFX/KZ/E/C/TE/S/CN | L | D | S | L | + | – | – | 229 | 7 |
SD015 | RT3 | ENR/LEV/CIP/ CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 23 |
SD016 | RT3 | ENR/LEV/CIP/ CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 25 |
SD004 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 28 |
SD007 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 26 |
SD008 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | qnrB | – | 228 | 26 |
SD012 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 26 |
SD014 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 27 |
SD019 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 22 |
SD023 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | qnrB | – | 228 | 22 |
SD024 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 21 |
SD029 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 20 |
SD030 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 24 |
SD035 | RT4 | ENR/LEV/CIP/ KZ/CRO/CTX/E/TE/CN | L | D | S | L | + | – | – | 228 | 23 |
SD001 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | – | + | 229 | 8 |
SD006 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | – | – | 229 | 8 |
SD009 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | – | – | 229 | 8 |
SD011 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | – | – | 229 | 9 |
SD013 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | – | – | 229 | 8 |
SD017 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | – | – | 229 | 8 |
SD018 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | – | – | 229 | 10 |
SD022 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | qnrS | – | 229 | 6 |
SD028 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | qnrS | – | 229 | 4 |
SD031 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | qnrS | – | 229 | 3 |
SD032 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | qnrS | – | 229 | 1 |
SD034 | RT5 | NOR/ENR/LEV/CIP/OFX/ KZ/CRO/CTX/E/C/TE/S/CN | L | N | I | L | + | qnrS | – | 229 | 2 |