Table 3 The number of synergistic and antagonistic combination with clarithromycin and imipenem in each clinical status
FIC index | |||
|---|---|---|---|
Synergy + Additive N = 14 (%) | Indifference + Antagonism N = 15 (%) | p value | |
Age | |||
< 65 years | 7 (24.1) | 7 (24.1) | 0.86 |
≥65 years | 7 (24.1) | 8 (27.6) | |
Sex | |||
Male | 6 (20.7) | 6 (20.7) | 0.88 |
Female | 8 (27.6) | 9 (31.0) | |
Smoking history | |||
Yes | 3 (10.3) | 6 (20.7) | 0.43 |
No | 11 (37.9) | 9 (31.0) | |
With bronchiectasis | |||
Yes | 4 (13.8) | 6 (20.7) | 0.70 |
No | 10 (34.5) | 9 (31.0) | |
With immunosuppression | |||
Yes | 10 (34.5) | 5 (17.2) | 0.040* |
No | 4 (13.8) | 10 (34.5) | |
Pretreatment of antibiotics | |||
Yes | 6 (20.7) | 8 (27.6) | 0.57 |
No | 8 (27.6) | 7 (24.1) | |
erm (41) gene status | |||
del + C28 | 10 (34.5) | 10 (34.5) | 0.78 |
T28 | 4 (13.8) | 5 (17.2) | |