Fig. 6

Map of adhesin genes and pseudogenes annotated in genotypes 1 and 2 M. haemolytica. The map is approximate and not to scale. Adhesin genes are represented with horizontal arrows that are solid yellow for genotype 1 strains and solid blue for genotype 2 strains. Pseudogenes are represented with striped horizontal arrows that are similarly color coded. Numbers below the genes and pseudogenes represent their nucleotide size. Black vertical arrows indicate homology of adhesin genes and/or pseudogenes between genotype 1 and 2 strains. The adhesin B gene of genotype 2 strains is split into two pseudogenes in genotype 1 strains. The adhesin B1 and B2 pseudogenes of the 1i strain (GenBank# CP017499) have greater genome separation from each other versus the other four genotype 1 strains due to an apparent genome inversion. The adhesin D gene was annotated to a similar size in genotype 1 and 2 strains by the NCBI prokaryotic genome annotation pipeline, however the D pseudogene in genotype 1 strains encodes multiple stop codons. The adhesin G gene of genotype 2 strains was not annotated or observed in genotype 1 strains. The adhesin E gene of all four genotype 2 strains is truncated in comparison to genotype 1 strains