Table 2 VMH simulation of tryptophan metabolism in intestinal flora
From: Role of tryptophan-metabolizing microbiota in mice diarrhea caused by Folium sennae extracts
Bacteria | Reactions | Score | Metabolites | ||
|---|---|---|---|---|---|
| Â | Abbreviation | Description | Â | Abbreviation | Description |
Streptococcus | 5HLTDL | 5-Hydroxy-L-Tryptophan Decarboxy-Lyase | 4 | Trp-L 5htrp | L-Tryptophan 5-Hydroxy-L-tryptophan |
LTDCL | L-Tryptophan Decarboxy-Lyase | 4 | |||
5HXKYNDCL | 5-Hydroxykynurenamine Decarboxy-Lyase | 1 | |||
EX_5htrp(e) | Exchange of 5-Hydroxy-L-Tryptophan | 1 | |||
EX_trp_L(e) | Exchange of L-Tryptophan | 1 | |||
ACACT1r | Acetyl Coenzyme A C-Acetyltransferase | 0 | |||
TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
Sutterella | FKYNH | N-Formyl-L-Kynurenine Amidohydrolase | 4 | Trp-L | L-Tryptophan |
EX_trp_L(e) | Exchange of L-Tryptophan | 1 | |||
TRPS1 | Tryptophan synthase (indoleglycerol phosphate) | 0 | |||
TRPS2 | tryptophan synthase (indole) | 0 | |||
TRPS3 | tryptophan synthase (indoleglycerol phosphate) | 0 | |||
TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
Dorea | EX_trp_L(e) | Exchange of L-Tryptophan | 1 | Trp-L | L-Tryptophan |
ANPRT | Anthranilate phosphoribosyltransferase | 0 | |||
ANS | Anthranilate synthase | 0 | |||
ANS2 | Anthranilate synthase 2 | 0 | |||
IGPS | Indole-3-glycerol-phosphate synthase | 0 | |||
PRAI | Phosphoribosylanthranilate isomerase | 0 | |||
TRPS1 | Tryptophan synthase (indoleglycerol phosphate) | 0 | |||
TRPS2 | tryptophan synthase (indole) | 0 | |||
TRPS3 | tryptophan synthase (indoleglycerol phosphate) | 0 | |||
TRPt2r | L-tryptophan reversible transport via proton symport | 0 | Â | Â | |
TRPTA | tryptophan transaminase | 0 | |||
Lactobacillus | EX_trp_L(e) | Exchange of L-Tryptophan | 1 | Trp-L | L-Tryptophan |
ACACT1r | Acetyl Coenzyme A C-Acetyltransferase | 0 | |||
TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
Mycoplasma | EX_trp_L(e) | Exchange of L-Tryptophan | 1 | Trp-L | L-Tryptophan |
TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
Adlercreutzia | EX_trp_L(e) | Exchange of L-Tryptophan | 1 | Trp-L | L-Tryptophan |
TRPt2r | L-tryptophan reversible transport via proton symport | 0 | |||
Paraprevotella | ANPRT | Anthranilate phosphoribosyltransferase | 0 | Trp-L | L-Tryptophan |
ANS | Anthranilate synthase | 0 | |||
ANS2 | Anthranilate synthase 2 | 0 | |||
IGPS | Indole-3-glycerol-phosphate synthase | 0 | |||
PRAI | Phosphoribosylanthranilate isomerase | 0 | |||
TRPS1 | Tryptophan synthase (indoleglycerol phosphate) | 0 | |||
TRPS2 | tryptophan synthase (indole) | 0 | |||
TRPS3 | tryptophan synthase (indoleglycerol phosphate) | 0 | |||
TRPTA | tryptophan transaminase | 0 | |||