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Table 2 List of circular bacteriocins identified with potential activity against clinically relevant isolates as part of the WHO’s Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics [44]

From: Bioinformatic prospecting and phylogenetic analysis reveals 94 undescribed circular bacteriocins and key motifs

Identified previously/in this studyPathogen potentially susceptibleBacteriocin producerExperimental anti-bacterial activity against clinically relevant bacteriaSource
Identified previouslyEnterococcus faeciumEnterococcus faecalis 39–5S. aureus, E. faecalis, E. faecium, S. agalactiae, S. sanguis[45]
Enterococcus faeciumEnterococcus faecalis subsp. liquefaciens S-48S. faecalis S-47, Escherichia coli U-9, E. faecalis OGlX[46, 47]
Enterococcus faeciumEnterococcus faecium NKR-5-3BB. coagulans, B. subtilis, L. lactis ssp. lactis, L. sakei ssp. sakei[48]
Staphylococcus aureusStaphylococcus aureus 4185B. cereus, B. coagulans, B. licheniformis, L. monocytogenes, M. luteus[49, 50]
Streptococcus pneumoniae/Group A/Group BStreptococcus uberis 42E. faecalis, E. hirae, M. luteus, S. aureus, S. agalactiae, S. salivarius, S. pyogenes, S. equisimilis, S. dysgalactiae, S. anginosus[29]
Identified in this studyEnterococcus faeciumEnterococcus villorum F1129DN/AThis study
Enterococcus faeciumEnterococcus thailandicus a523N/AThis study
Enterococcus faeciumEnterococcus faecium E8172N/AThis study
Enterococcus faeciumEnterococcus faecium IHC105N/AThis study
Enterococcus faeciumEnterococcus faecalis AZ19N/AThis study
Staphylococcus aureusStaphylococcus felis F9N/AThis study
Staphylococcus aureusStaphylococcus felis F21N/AThis study
Staphylococcus aureusStaphylococcus xylosus INIFAP 004–15N/AThis study
Staphylococcus aureusStaphylococcus kloosii SNUC 4696N/AThis study
Staphylococcus aureusStaphylococcus aureus 3688STDY6124959N/AThis study
Staphylococcus aureusStaphylococcus epidermidis AU23N/AThis study
Streptococcus pneumoniae/Group A/Group BStreptococcus uberis NCTC 4674N/AThis study
Streptococcus pneumoniae/Group A/Group BStreptococcus suis YS111N/AThis study
Streptococcus pneumoniae/Group A/Group BStreptococcus sp. OBRC6N/AThis study
Streptococcus pneumoniae/Group A/Group BStreptococcus gordonii BCA7N/AThis study
Streptococcus pneumoniae/Group A/Group BStreptococcus cristatus 787_SOLIN/AThis study
Streptococcus pneumoniae/Group A/Group BStreptococcus sp. CCH8-G7N/AThis study
Streptococcus pneumoniae/Group A/Group BStreptococcus mitis KCOM 1350N/AThis study
Streptococcus pneumoniae/Group A/Group BStreptococcus pneumoniae UoS2029N/AThis study
Streptococcus pneumoniae/Group A/Group BStreptococcus thermophilus NCTC 12958N/AThis study
Streptococcus pneumoniae/Group A/Group BStreptococcus pneumoniae Zo 18 m39–2N/AThis study