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Table 2 Metabolism and enzyme GO terms significantly enriched in S. maltophilia JV3-specific response (VSR) genes

From: Identification and characterization of differentially expressed genes in Caenorhabditis elegans in response to pathogenic and nonpathogenic Stenotrophomonas maltophilia

GO category

Term

Count

%

FDR

Biological process

single-organism metabolic process

49

22.68

2.47E-06

 Small molecule metabolic process

27

12.5

5.27E-04

  organic acid metabolic process

22

10.19

1.64E-05

   carboxylic acid metabolic process

21

9.72

2.21E-05

    monocarboxylic acid metabolic process

18

8.33

8.53E-07

     flavonoid glucuronidation

14

6.48

3.02E-09

 flavonoid biosynthetic process

14

6.48

3.02E-09

 oxidation-reduction process

21

9.72

0.0433

transition metal ion transport

7

3.24

0.0468

Molecular function

catalytic activity

89

41.20

0.00174

 transferase activity, transferring glycosyl groups

17

7.87

0.00203

  transferase activity, transferring hexosyl groups

14

6.48

1.76E-07

   glucuronosyltransferase activity

12

5.56

9.70E-06

  UDP-glycosyltransferase activity

16

7.41

0.00155

carboxylic ester hydrolase activity

11

5.09

7.24E-04

Cellular component

extracellular region

20

9.26

0.0295

  1. Gene ontology (GO) enrichment analysis was performed on the VSR genes using DAVID Bioinformatics Resources 6.8. Of the 225 VSR genes, 216 were identified in DAVID and considered for analysis. GO analysis identifies terms relating to the biological process, molecular function, or cellular component that are significantly enriched among a list of genes. Indented terms indicate child terms, or subcategories, of the term listed above, with the parent term left-aligned. Note that the degree of indention of each term does not reflect absolute GO term level within each category. Count is the number of genes corresponding to each GO term. Percent is the count/216 total analyzed. FDR is the false discovery rate-corrected EASE enrichment score to account for multiple testing. Only terms with FDR <0.05 and the most descriptive term for each unique gene list are shown