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Table 2 Metabolism and enzyme GO terms significantly enriched in S. maltophilia JV3-specific response (VSR) genes

From: Identification and characterization of differentially expressed genes in Caenorhabditis elegans in response to pathogenic and nonpathogenic Stenotrophomonas maltophilia

GO category Term Count % FDR
Biological process single-organism metabolic process 49 22.68 2.47E-06
 Small molecule metabolic process 27 12.5 5.27E-04
  organic acid metabolic process 22 10.19 1.64E-05
   carboxylic acid metabolic process 21 9.72 2.21E-05
    monocarboxylic acid metabolic process 18 8.33 8.53E-07
     flavonoid glucuronidation 14 6.48 3.02E-09
 flavonoid biosynthetic process 14 6.48 3.02E-09
 oxidation-reduction process 21 9.72 0.0433
transition metal ion transport 7 3.24 0.0468
Molecular function catalytic activity 89 41.20 0.00174
 transferase activity, transferring glycosyl groups 17 7.87 0.00203
  transferase activity, transferring hexosyl groups 14 6.48 1.76E-07
   glucuronosyltransferase activity 12 5.56 9.70E-06
  UDP-glycosyltransferase activity 16 7.41 0.00155
carboxylic ester hydrolase activity 11 5.09 7.24E-04
Cellular component extracellular region 20 9.26 0.0295
  1. Gene ontology (GO) enrichment analysis was performed on the VSR genes using DAVID Bioinformatics Resources 6.8. Of the 225 VSR genes, 216 were identified in DAVID and considered for analysis. GO analysis identifies terms relating to the biological process, molecular function, or cellular component that are significantly enriched among a list of genes. Indented terms indicate child terms, or subcategories, of the term listed above, with the parent term left-aligned. Note that the degree of indention of each term does not reflect absolute GO term level within each category. Count is the number of genes corresponding to each GO term. Percent is the count/216 total analyzed. FDR is the false discovery rate-corrected EASE enrichment score to account for multiple testing. Only terms with FDR <0.05 and the most descriptive term for each unique gene list are shown