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Table 1 The geographical region of the isolation, species identification, antifungal susceptibility profile, genotype and sequence type of 8 C. gattii strains

From: Clinical and microbiological characteristics of Cryptococcus gattii isolated from 7 hospitals in China

Isolate No.

ID by VITEK 2 Compact

pigmentation on CGB agar

ID by MALDI-TOF MS

geographical region of the isolation

STs

Genotype

5-FU

AMB

FCA

ITR

VRC

PSZ

(Identification rate)

(score)

a

b

a

b

a

b

a

b

a

b

b

1

C. neoformans (93%)

blue

C. gattii (2.190)

temperate regions

20

VGII

< 4

2

< 0.5

1

8

32

0.25

0.25

0.25

0.25

0.25

2

C. neoformans (90%)

blue

C. gattii (2.043)

tropical areas

106

VGI

< 4

0.5

< 0.5

0.25

1

4

< 0.125

0.06

0.06

0.06

0.06

3

C. neoformans (96%)

blue

C. gattii(2.275)

subtropical area

57

VGI

< 4

0.5

< 0.5

0.25

1

4

< 0.125

0.12

0.06

0.12

0.12

4

C. neoformans (99%)

blue

C. gattii (2.092)

subtropical area

197

VGI

< 4

1

< 0.5

0.25

2

4

< 0.125

0.06

< 0.125

0.06

0.12

5

C. neoformans (86%)

blue

C. gattii (2.118)

temperate regions

57

VGI

< 4

0.5

< 0.5

0.25

2

4

< 0.125

0.12

0.06

0.06

0.12

6

C. neoformans (91%)

blue

C. gattii (2.126)

tropical areas

7

VGII

< 4

2

< 0.5

0.5

8

128

0.25

0.25

0.25

0.25

0.5

7

C. neoformans (98%)

blue

C. gattii (2.188)

subtropical area

57

VGI

< 4

0.5

< 0.5

0.25

1

4

< 0.125

0.06

0.06

0.06

0.12

8

C. neoformans (99%)

blue

C. gattii (2.194)

temperate regions

161

VGI

< 4

1

< 0.5

0.25

2

4

< 0.125

0.12

0.06

0.06

0.12

  1. Notes: a and b represented the method of ATB fungus 3 and Yeast one respectively; the abbreviations for antifungal drugs were: 5-FU 5-Flucytosine, AMB Amphotericin B, FCA Fluconazole, ITR Itraconazole, VRC Voriconazole, PSZ Posaconazole