The influence of blood on the human gut microbiome

BMC Microbiology

Table 2 Taxa from published studies on various diseases that we also found in our study

	Direction of variation in abundance in article	Direction of variation in abundance in our analysis (Blood vs Control)
Flemer et al. (2017)
Colorectal cancer vs control
Bacteroides	↑	↑
Roseburia	↑	↓(faecis)
Ruminococcus	↑	↓
Zackular et al. (2014)
Adenoma vs control
Ruminococcaceae	↑	↓
Clostridium	↑/↓^a	↑
Bacteroides	↓	↑
Lachnospiraceae	↓	↓
Clostridiales	↓	↓
Carcinoma vs control
Lachnospiriaceae	↑/↓^a	↓
Enterobacteriaceae	↑	↑
Bacteroides	↓	↑
Clostridiales	↓	↓
Gevers et al. (2014)
Crohn’s disease vs control
Enterobacteriaceae	↑	↑
Bacteroides	↓	↓
Clostridiales	↓	↓
Erysipelotrichaceae	↓	↑
Faecalibacterium	↓	↓
Roseburia	↓	↓(feacis)
Blautia	↓	↓(obeum)
Ruminococcus	↓	↓
Coprococcus	↓	↓
Forbes et al. (2018)
All diseases vs control
Eggerthella	↑	↑
Clostridium	↑	↑
Gemmiger	↓	↓
Lachnospira	↓	↓
Crohn’s disease vs control
Blautia	↑	↓(obeum)
Ulcerative colitis
Clostridium	↑/↓^a	↑
Coprococcus	↓	↓
Ruminococcus	↓	↓
Multiple sclerosis vs control
Erysipelotrichaceae	↑	↑
Rheumatoid arthritis vs control
Roseburia	↓	↓(faecis)

↓ = decreased abundance in altered state. ↑ = increased abundance in altered state. () = we found a significant variation in the specific species from the genera but not in the genera itself. ^a = the authors found augmentation and diminution in abundance of OTUs associated with the same genus

ISSN: 1471-2180