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Table 6 Univariable logistic regression analysis of the association between age and resistance class of commensal E. coli stratified by policy implementation interval

From: Antimicrobial use policy change in pre-weaned dairy calves and its impact on antimicrobial resistance in commensal Escherichia coli: a cross sectional and ecological study

Period

Age

Cross tabulations

Odds ratio and (95% CI)

 

TET

XNL+

NAL+

CIP+NAL+XNL+

XNL+

NAL+

CIP+NAL+XNL+

Pre Policy Implementation (May-Aug)

57 - 80d

10

1

3

0

   

43 - 56d

5

4

8

1

8 (2.4 – 26.6)

5.3 (2.2 – 13.0)

2 (0.4 – 8.9)

29 - 42d

1

4

13

5

40 (8.9 - 179)

43.3 (13 – 143.8)

50 (4.1 – 609.1)

15 - 28d

4

5

2

9

12.5 (3.8 – 41.5)

1.7 (0.6– 5.7)

22.5 (6.8 – 74.7)

1 - 14d

2

12

0

12

60 (16.4 – 220.6)

1.7 (0.4 – 6.9)

60 (16.4 – 220.6)

During Policy Implementation (Sep-Nov 15)

57 - 80d

18

2

12

4

   

43 - 56d

13

1

23

3

0.7 (0.2 – 2.6)

2.7 (1.6 – 4.5)

1 (0.4 – 2.2)

29 - 42d

15

4

20

5

2.4 (1.0 – 5.9)

2 (1.2 – 3.3)

1.5 (0.7 – 3.3)

15 - 28d

7

8

12

12

10.3 (4.2 – 25.3)

2.6 (1.4 – 4.7)

7.7 (3.8 – 15)

1 - 14d

2

19

0

18

85.5 (28.5 – 256.9)

0.8 (0.2 – 2.9)

40.5 (16.5 – 99.6)

Post Policy Implementation (Nov 15-Jan)

57 - 80d

35

11

2

10

   

43 - 56d

26

11

5

6

1.3 (0.8 – 2.1)

3.4 (1.4 – 8.4)

0.8 (0.4 – 1.5)

29 - 42d

12

3

19

10

0.8 (0.4 – 1.6)

27.7 (12.4 – 61.6)

2.9 (1.8 – 4.8)

15 - 28d

4

8

0

36

6.4 (3.2 – 12.9)

4.4 (1.2 – 16.1)

31.5 (17.3 – 57.4)

1 - 14d

20

21

4

2

3.3 (2.0 – 5.4)

3.5 (1.4 – 8.6)

0.4 (0.2 – 0.9)

  1. OR and 95% confidence intervals that exclude the null value of 1 are highlighted in bold.