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Table 2 MIC and mutation of each generation of strains

From: Evolution of resistance mechanisms and biological characteristics of rifampicin-resistant Staphylococcus aureus strains selected in vitro

Strains

Generations

 

0th

1th

2th

3th

4th

5th

6th

7th

8th

SA247R

MIC

0.25

0.25

1

2

4

4

8

32

128

Mutation

–

–

–

H481L

H481L

H481L

H481L

H481F

H481F

SA252R

MIC

0.25

0.25

0.5

2

4

8

16

64

128

Mutation

–

–

–

–

–

–

H481Y

H481Y

H481Y

SA1370R

MIC

0.25

0.25

0.5

1

2

8

16

32

128

Mutation

–

–

–

–

–

–

S464P

H481Y/S464P

H481Y/S464P

ATCC 25923R

MIC

0.25

0.25

1

2

4

16

32

64

128

Mutation

–

–

–

R484H

S464P

S464P

S464P

H481Y/S464P

H481Y/S464P

  1. MIC minimum inhibitory concentration, mg/L; H Histidine; L Leucine; F Phenylalanine; Y Tyrosine; S Serine; P Proline; R Arginine
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BMC Microbiology

ISSN: 1471-2180

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