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Table 4 Statistical analyses of associations between the presence or absence of virulence factors and cytotoxicity on Caco-2 cells

From: Toxigenic potential and antimicrobial susceptibility of Bacillus cereus group bacteria isolated from Tunisian foodstuffs

F-test t-test
Significant association tested
Cytotoxicity versus virulence factors
Sum Sq p-value Significant association tested
Cytotoxicity versus Presenceb/ Absencea of virulence factors
Estimate p-value
Cytotoxicity after Cytotoxicity after Cytotoxicity after Cytotoxicity after
18 h 5d 18 h 5d 18 h 5d 18 h 5d
hblC:hblD 5562 20,994 0.0032 ** 4.57E-08 *** hblC b :hblD b ND 14 ND 4.75E-08 ***
hblC a :hblD b -10 ND 0.0034 * ND
hblC:nheB 13,568 10,441 1.58E-07 *** 0.0005 *** hblC b :nheB b 27 24 1.58E-07 *** 0.0073 **
hblC a :nheB b ND −17 ND 0.0058 **
hblC:nheC 6497 11,695 0.0002 *** 4.08E-05 *** hblC b :nheC b 12 14 0.0003 *** 4.08E-05 ***
hblD:nheC 3675 11,106 0.0058 ** 6.33E-05 *** hblD b :nheC b −8 −14 0.0058 ** 6.33E-05 ***
bceT: hblB 23,036 8048 1.12E-10 *** 0.0006 *** bceT b :hblB b 18 10 0.0002 *** 0.0006 ***
bceT a :hblB b −16 ND 3.07E-07 *** ND
nheC:bceT:hblB 11,787 6560 6.14E-06 *** 0.0085 ** nheC b :bceT b :hblB b −17 ND 0.0004 *** ND
nheC b :bceT a :hblB b 9 ND 0.004 ** ND
nheC b :bceT b :hblB a ND 6 ND 0.012 *
bceT:hblD 11,867 ND 8.99E-07 *** ND bceT b :hblD b −6 ND 8.99E-07 *** ND
bceT:nheC 4733 ND 0.0017 ** ND bceT b :nheC b −12 ND 0.0017 ** ND
ces:hblC 9828 ND 7.46E-06 *** ND ces b :hblC b −17 ND 7.46E-06 *** ND
cytK:hblD 19,045 ND 6.51E-10 *** ND cytK b :hblD b 14 ND 6.51E-10 *** ND
cytK:nheC 6617 ND 0.0002 *** ND cytK b :nheC b −12 ND 0.0002 *** ND
cytK:nheC:hblB 4501 ND 0.0095 ** ND cytK b :nheC a :hblB b 12 ND 0.011 * ND
hblC:cytK 15,874 ND 1.53E-08 *** ND hblC b :cytK b −12 ND 1.53E-08 *** ND
hblD:hblA 2417 ND 0.025 * ND hblD b :hblA b −8 ND 0.025 * ND
nheB:nheC 6500 ND 0.0012 ** ND nheB a :nheC b 27 ND 0.01 * ND
nheB b :nheC b −9 ND 0.018 * ND
bceT:hblA ND 8530 ND 0.002 ** bceT b :hblA b ND −7 ND 0.0008 ***
hblC:hblB ND 5000 ND 0.007 ** hblC b :hblB b ND −11 ND 0.007 **
nheA:hblB ND 8433 ND 0.002 ** nheA a :hblB b ND −29 ND 0.047 *
nheA b :hblB b ND 11 ND 0.025 *
cytK:hblA 3400 ND 0.029 * ND cytK b :hblA b NS ND > 0.05 ND
cytK a :hblA b NS ND > 0.05 ND
cytK:nheC:hblA 3165 ND 0.0375 * ND cytK b :nheC b :hblA b NS ND > 0.05 ND
cytK a :nheC b :hblA b NS ND > 0.05 ND
  1. aabsence; bpresence; ND Not determined; NS Not significant (p-value≥0.05); *: significant (p-value: 0.01 to 0.05); **: very significant (p-value: 0.001 to 0.01); ***: very significant (p-value < 0.001)