Table 2 Risk factors and treatment outcome of patients with candidemia in Teaching Hospital Kandy
Candidemia (n = 110) | |||
|---|---|---|---|
Parameters | C. albicans (n = 34) | Non albicans (n = 76) | Odds ratio confident interval (95%) and P value |
Age | – | – | > 0.05 |
Gender male: female | 1.2:0.8 | 1.3:0.7 | > 0.05 |
Clinical risk factors | |||
Diabetes | 26 (23.6%) | 19 (25%) | > 0.05 |
Liver failure | 12 (11%) | 19 (25%) | > 0.05 |
Chronic lung diseases | 15 (13.6%) | 16 (21%) | > 0.05 |
Renal failure | 12 (35.2%) | 18 (24.3%) | > 0.05 |
Solid organ malignancy | 7 (20.6%) | 12 (16.2%) | > 0.05 |
Hematological malignancies | 6 (17.6%) | 16 (21%) | > 0.05 |
Exposure of broad spectrum antibiotics | 28 (82.3%) | 56 (73.7%) | > 0.05 |
Exposure of anti-fungal | 3 (8.8%) | 38 (50%) | 2.2 (1.9–3.2); 0.03 |
Under gone abdominal surgeries | 7 (20.6%) | 19 (25%) | > 0.05 |
On immune suppressive medications | 6 (17.6%) | 38 (50%) | 2.4 (2.1–2.9); 0.04 |
On hemodialysis | 12 (35.2%) | 22 (29.7%) | > 0.05 |
Prolonged intensive care stay ≥14 days | 8 (23.5%) | 56 (73.7%) | 3.3 (2.2–4.5); 0.03 |
On central venous line > 8 days | 16 (47.0%) | 64 (84.2%) | 4.3 (3.4–5.4); 0.03 |
On urinary catheters > 10 days | 18 (52.9%) | 38 (50%) | > 0.05 |
Mechanical ventilation | |||
Presence of prosthesis or implant | 12 (35.5%) | 26 (35.5%0 | > 0.05 |
Total parenteral nutrition | 6 (17.6%) | 16 (21%) | > 0.05 |
Candiduria | 6 (17.6%) | 16 (21%) | > 0.05 |
6 (17.6%) | 12 (15.7%) | > 0.05 | |
Duration of treatment | 16.8 ± 2.2 days | 26.8 ± 2.2 days | 0.03 |
Out come | |||
Complete recovery | 28 (82.3%) | 48 (63.1%) | 0.04 |
Death | 6 (17.7%) | 28 (36.9%) | 0.04 |
Day 7 | 2 (33.3%) | 18 (64.2%) | 0.03 |
Day 30 | 4 (66.6%) | 10 (35.8%) | 0.04 |