Table 2 Changes in SP2–6 metabolites after exposure to different fungicides
From: Use of GC–MS based metabolic fingerprinting for fast exploration of fungicide modes of action
Mode of action group | Fungicides | Number of metabolites changed (up, down) | |
|---|---|---|---|
Specifically changed | Commonly changed | ||
β-tubulins assembly | Carbendazim | 50 (48, 2) | 8 (7, 1) |
Thiophanatemethyl | 24 (16, 8) | ||
Respiration | Boscalid | 27 (15, 12) | 11 (6, 5) |
Kresoxim-methyl | 26 (22, 4) | ||
Fluazinam | 66 (62, 4) | ||
Mitochondrial function | Cyprodinil | 4 (1, 3) | 17 (1, 16) |
Pyrimethanil | 8 (1, 7) | ||
Signal transduction | Procymidone | 22 (21, 1) | 25 (15, 10) |
Fludioxonil | 55 (44, 11) | ||
Membrane sterol biosynthesis | Fenhexamid | 14 (10, 4) | 7 (2, 5) |
Imazalil | 4 (2, 2) | ||
Multi site action | Chlorothalonil | 83 (65,18) | n.a. |
Thiram | 37 (15, 22) | n.a. | |
Unknown | SYP-14288 | 20 (15,5) | n.a. |