Table 1 List of 25 most up-regulated genes in the transcriptome of B. thailandensis strain E555 during infection of macrophages after 6 h post-infection
Bt E555 fig|869,728.6. peg. | log2 fold change in T6 transcriptome | Bt E555 gene function assigned by RAST | Bp Sanger ID | Bp gene name | Bp gene product | Significantly upregulated in T5 transcriptome? | Significantly upregulated in T6 proteome? |
|---|---|---|---|---|---|---|---|
5909 | 11.7106 | Hcp | BPSS1498 | tssD-5 (hcp1) | type VI secretion system protein TssD-5 | Yes | Yes |
5896 | 9.5536 | N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) | BPSS1490 | – | N-acetylmuramoyl-L-alanine amidase | Yes | Yes |
5907 | 9.3004 | Uncharacterized protein ImpB | BPSS1496 | tssB-5 | type VI secretion system protein TssB-5 | Yes | Yes |
5908 | 9.0842 | Uncharacterized protein ImpC | BPSS1497 | tssC-5 | type VI secretion system protein TssC-5 | Yes | Yes |
5910 | 8.9729 | Uncharacterized protein similar to VCA0109 | BPSS1499 | tssE-5 | type VI secretion system protein TssE-5 | Yes | Â |
5897 | 8.5387 | Plasmid pIB6 ORFA DNA | BPSS1491 | – | hypothetical protein | Yes | Yes |
2756 | 8.4671 | TonB-dependent hemin, ferrichrome receptor | BPSS0244 | – | BhuR (Outer membrane heme receptor) | Yes | No |
5913 | 8.4574 | ClpB protein | BPSS1502 | tssH-5 | type VI secretion system protein TssH-5 | Yes | No |
5911 | 8.1660 | Protein ImpG/VasA | BPSS1500 | tssF-5 | type VI secretion system protein TssF-5 | Yes | No |
3093 | 8.0481 | SyrP-like protein | BPSL1785 | – | hypothetical protein | Yes | Yes |
3100 | 7.8577 | ABC-type siderophore export system, fused ATPase and permease components | BPSL1779 | – | siderophore biosynthesis related ABC transport protein | Yes | No |
3113 | 7.4295 | Non-ribosomal peptide synthetase modules, pyoverdine | BPSL1778 | – | siderophore related no-ribosomal peptide synthase | No | No |
5914 | 7.3994 | VgrG protein | BPSS1503 | tssI-5 | type VI secretion protein TssI-5 | Yes | No |
5915 | 7.2906 | hypothetical protein | BPSS1504 | tagAB-5 | type VI secretion system-associated protein TagAB-5 | Yes | Yes |
5839 | 7.2027 | Fig. 00464790: hypothetical protein | BPSL3352 | – | hypothetical protein | Yes |  |
5920 | 7.1177 | Uncharacterized protein ImpJ/VasE | BPSS1509 | tssK-5 | type VI secretion system protein TssK-5 | Yes | Yes |
5922 | 7.0900 | IcmF-related protein | BPSS1511 | tssM-5 | type VI secretion system protein TssM-5 | Yes | Yes |
6277 | 7.0886 | Hemin uptake protein | BPSS0362 | – | hypothetical protein | Yes | No |
3095 | 6.9269 | Ferrichrome transport system permease protein FhuB (TC 3.A.1.14.3) | BPSL1783 | – | iron-hydroxamate transporter permease subunit | No | No |
5952 | 6.7155 | Type III secretion thermoregulatory protein (LcrF,VirF,transcription regulation of virulence plasmid) | BPSS1546 | bsaN | regulator of type III secretion system effector proteins BsaN (T3SS-3) | Yes | No |
5900 | 6.4369 | Fig. 00456189: hypothetical protein | no homolog |  |  | Yes | No |
5899 | 6.4344 | Autotransporter adhesin | BPSS1492 | bimA | Burkholderia intracellular motility A, BimA | Yes | Yes |
5919 | 6.1933 | putative lipoprotein | BPSS1508 | tssJ-5 | type VI secretion system protein TssJ-5 | Yes | Yes |
3092 | 6.1826 | hypothetical MbtH-like protein, PA2412 homolog | BPSL1786 | – | hypothetical protein | Yes | No |
5927 | 6.1495 | DNA-binding response regulator | BPSS1522 | bprB | two-component response regulator | Yes | No |