Table 1 CpG motifs and copy numbers in the whole genome of LAB strains. Copy number of typical CpG motifs in the whole genome of L. lactis LC-Plasma, L. rhamnosus ATCC 53103, and NCC2706 were determined as described in Methods
Bacterial strains | |||||
|---|---|---|---|---|---|
Lactococcus lactis LC-Plasma | Lactobacillus rhamnosus ATCC 53103 | Bifidobacterium longum NCC2705 | |||
pDC activating | RRCGRYCGYY | 51 | 195 | 288 | |
RYCGYRTCGYR | 8 | 54 | 139 | ||
RYCGRY | 3072 | 17,681 | 25,057 | ||
B cell activating | optimal for mice | RRCGYY | 4691 | 13,169 | 13,118 |
optimal for human | GTCGTT | 882 | 1534 | 1295 | |
CpG hexamer | NNCGNN | 61,462 | 180,144 | 240,176 | |