Fig. 3

Correlation between the copy numbers of CpG motifs and immunostimulatory activity in 200 bp DNA fragments stratified by G + C contents. Fragments in Fig. 2 are stratified by G + C contents. a Each dot depicts an independent 200 bp amplified from the LC-Plasma genomic regions with G + C < 40% shown in Fig. 2. b Each dot depicts an independent 200 bp amplified from the LC-Plasma genomic regions with G + C ≥ 40%. c 200 bp DNA fragments amplified from the LC-Plasma genomic regions were stratified into 5 groups based on the copy numbers of CpG motifs and their pDCs stimulatory activities were compared. Bar depicts the standard deviation (S.D.). Bars with different notation exhibit significant differences (* p < 0.05, ** p < 0.01)