Table 1 Extracellular and intracellular MIC endpoints for 5 antimicrobials against two Brazilian L. intracellularis isolates. The bacteria were prepared independently and tested twice. The endpoint was obtained from 3 replicates of each passage. Minimum Inhibitory Concentration (MIC) μg/ml
Antimicrobials | Minimum Inhibitory Concentration (MIC) μg/ml | |||
|---|---|---|---|---|
BRPHE01_E5 Passages 13–14 | BRPHE02_E8 Passages13–14 | |||
Intracellular activity | Extracellular activity | Intracellular activity | Extracellular activity | |
1. Chlortetracycline | 32–64 | 32–64 | 8–16 | 64 |
2. Lincomycin | > 128 | > 128 | > 128 | > 128 |
3. Tiamulin | ≤0.125 | 1–2 | 1–2 | 0.5 |
4. Tylosin | 2–8 | > 128 | 2 | 16–32 |
5. Valnemulin | ≤0.125 | ≤0.125 | ≤0.125 | ≤0.125 |