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Table 1 Extracellular and intracellular MIC endpoints for 5 antimicrobials against two Brazilian L. intracellularis isolates. The bacteria were prepared independently and tested twice. The endpoint was obtained from 3 replicates of each passage. Minimum Inhibitory Concentration (MIC) μg/ml

From: Isolation and in vitro antimicrobial susceptibility of porcine Lawsonia intracellularis from Brazil and Thailand

Antimicrobials Minimum Inhibitory Concentration (MIC) μg/ml
  BRPHE01_E5
Passages 13–14
BRPHE02_E8
Passages13–14
  Intracellular activity Extracellular activity Intracellular activity Extracellular activity
1. Chlortetracycline 32–64 32–64 8–16 64
2. Lincomycin > 128 > 128 > 128 > 128
3. Tiamulin ≤0.125 1–2 1–2 0.5
4. Tylosin 2–8 > 128 2 16–32
5. Valnemulin ≤0.125 ≤0.125 ≤0.125 ≤0.125