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Fig. 2 | BMC Microbiology

Fig. 2

From: In vitro synergy of sertraline and tetracycline cannot be reproduced in pigs orally challenged with a tetracycline resistant Escherichia coli

Fig. 2

Indicator E. coli CFU Numbers (in log10 numbers of CFU per gram feces (_F) or ileum (_I)) of an indicator E. coli strain at three different time points in four different treatment groups. Vertical bars indicate standard deviations. Before the pigs were inoculated with the indicator strain, no pigs carried a detectable level of the indicator strain in feces (data not shown on the figure). Time point T(0) refers to the first treatment day. Fecal and ileum samples were obtained prior to the first treatment at the same day. From each group 12 individual fecal samples were obtained. Hereafter, two pigs were euthanized and ileum samples were obtained from 2X4 pigs. Time T(7) refers to 48 h after the last of five days of treatment. From each group 10 individual fecal samples were obtained. Hereafter, five pigs were euthanized at ileum samples were obtained from 5X4 pigs. Time T(15) refers to nine days after the last of five days of treatment. From each group five individual fecal samples were obtained. Hereafter, the five pigs in each group were euthanized and ileum samples were obtained from 5X4 pigs. For visual purposes all CFU count at the different time points has been included in the same figure, statistical analysis were, however, done for each time point and sampling site individually. The asterisk indicate that the ileum samples from the tetracycline treated group had a significant higher level than ileum samples from the three other groups at time point T(7)

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