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Table 3 PBMC cytokine levels in response to co-culturing with L. brevis BBE-Y52 or S. mutans

From: Characterization of a Lactobacillus brevis strain with potential oral probiotic properties

Cytokine

aPBMCs

bPBMCs + S. mutans

Control

BBE-Y52

S. mutans

Control

BBE-Y52

IL-10 (pg mL− 1)

164 ± 2

186 ± 2

177 ± 4

248 ± 2

243 ± 3

IL-12p70 (pg mL− 1)

28 ± 2

31 ± 1

33 ± 1

65 ± 2

59 ± 2

IL-10/IL-12p70

5.8 ± 0.2

6.1 ± 0.1*

5.4 ± 0.1*

3.8 ± 0.1

4.1 ± 0.1*

  1. a, PBMCs incubated either alone (control) or with BBE-Y52/S. mutans for 12 h; b, S. mutans treated PBMCs was incubated either alone (control) or with BBE-Y52 for 24 h; * IL-10-to-IL-12p70 ratio was significant (P < 0.05) based on Student’s t-test
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BMC Microbiology

ISSN: 1471-2180

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