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Table 3 PBMC cytokine levels in response to co-culturing with L. brevis BBE-Y52 or S. mutans

From: Characterization of a Lactobacillus brevis strain with potential oral probiotic properties

Cytokine aPBMCs bPBMCs + S. mutans
Control BBE-Y52 S. mutans Control BBE-Y52
IL-10 (pg mL− 1) 164 ± 2 186 ± 2 177 ± 4 248 ± 2 243 ± 3
IL-12p70 (pg mL− 1) 28 ± 2 31 ± 1 33 ± 1 65 ± 2 59 ± 2
IL-10/IL-12p70 5.8 ± 0.2 6.1 ± 0.1* 5.4 ± 0.1* 3.8 ± 0.1 4.1 ± 0.1*
  1. a, PBMCs incubated either alone (control) or with BBE-Y52/S. mutans for 12 h; b, S. mutans treated PBMCs was incubated either alone (control) or with BBE-Y52 for 24 h; * IL-10-to-IL-12p70 ratio was significant (P < 0.05) based on Student’s t-test