Table 1 In vitro susceptibility of C. albicans biofilms to antifungals
Strains | SMIC50 of antifungals (μg/ml) | |||
|---|---|---|---|---|
6 h | 12 h | 24 h | 36 h | |
amphotericin B | ||||
 CAI4-pCaEXP | 1 | 0.5 | 1 | 0.25 |
 CYR1OE | 4 | 8 | > 16 | 16 |
 PDE2OE | 4 | 4 | 1 | 16 |
caspofungin | ||||
 CAI4-pCaEXP | 0.125 | > 8 | > 8 | > 8 |
 CYR1OE | 0.125 | > 8 | > 8 | > 8 |
 PDE2OE | 8 | > 8 | > 8 | > 8 |
itraconazole | ||||
 CAI4-pCaEXP | > 16 | > 16 | > 16 | > 16 |
 CYR1OE | > 16 | > 16 | > 16 | > 16 |
 PDE2OE | > 16 | > 16 | > 16 | > 16 |
terbinafine | ||||
 CAI4-pCaEXP | > 256 | > 256 | > 256 | > 256 |
 CYR1OE | > 256 | > 256 | > 256 | > 256 |
 PDE2OE | > 256 | > 256 | > 256 | > 256 |