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Fig. 6 | BMC Microbiology

Fig. 6

From: The possible molecular mechanisms of farnesol on the antifungal resistance of C. albicans biofilms: the regulation of CYR1 and PDE2

Fig. 6

The expression of CYR1 protein in C. albicans biofilms. A: WT: Farnesol untreated wild strain (CAI4-pCaEXP); WT + F: Farnesol treated wild strain (CAI4-pCaEXP); C: Farnesol untreated CYR1-overexpressing strain (CYR1OE); C + F: Farnesol treated CYR1-overexpressing strain (CYR1OE). a and b: Farnesol decreased the expression of CYR1 of the CAI4-pCaEXP strain at 12, 24 and 36 h biofilm phases and decreased the expression of CYR1 of the CYR1OE strain at 6, 12 and 24 h biofilm phases compared to the respective untreated controls. Shown are means ± standard deviation of three independent experiments performed in duplicate. One-way analysis of variance (ANOVA) was employed to assess the statistical significance of differences in matched groups, while paired t-tests were performed for intra-group comparisons. *: p < 0.05. **: p < 0.01

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