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Table 1 Demographic and clinical characteristics of patients and controls

From: Changes in gut microbiota and plasma inflammatory factors across the stages of colorectal tumorigenesis: a case-control study

 

CRC (n = 130)

A-CRA (n = 88)

polyps (n = 62)

controls (n = 130)

P Value

Gender

 Male

65 (50.0%)

55 (62.5%)

31 (50.0%)

65 (50.0%)

0.228

 Female

65 (50.0%)

33 (37.5%)

31 (50.0%)

65 (50.0%)

Age(years)a

60.5 (9.8)

59.6 (10.3)

56.5 (8.9)

58.6 (8.9)

0.045

BMI (kg/m2)

  < 24.0

69 (53.1%)

44 (50.0%)

30 (48.4%)

74 (56.9%)

0.299

 24.0-27.9

51 (39.2%)

34 (38.6%)

20 (32.3%)

43 (33.1%)

  ≥ 28.0

10 (7.7%)

10 (11.4%)

12 (19.4%)

13 (10.0%)

Alcohol drinking

 Never

98 (75.4%)

61 (69.3%)

50 (80.6%)

109 (83.8%)

0.069

 Ever

32 (24.6%)

27 (30.7%)

12 (19.4%)

21 (16.2%)

Smoking

 Never

91 (70.0%)

54 (61.4%)

42 (67.7%)

105 (80.8%)

0.015

 Ever

39 (30.0%)

34 (38.6%)

20 (32.3%)

25 (19.2%)

Lesion location

 Proximal

45 (34.6%)

27 (30.7%)

30 (48.4%)

–

0.072

 Distal

85 (65.4%)

61 (69.3%)

32 (51.6%)

–

Hypertension

 No

89 (68.5%)

58 (65.9%)

45 (72.6%)

88 (67.7%)

0.854

 Yes

41 (31.5%)

30 (34.1%)

17 (27.4%)

42 (32.3%)

Heart Disease

 No

122 (93.8%)

83 (94.3%)

59 (95.2%)

128 (98.5%)

0.223

 Yes

8 (6.2%)

5 (5.7%)

3 (4.8%)

2 (1.5%)

Diabetes

 No

117 (90.0%)

80 (90.9%)

59 (95.2%)

120 (92.3%)

0.658

 Yes

13 (10.0%)

8 (9.1%)

3 (4.8%)

10 (7.7%)

  1. aAge was shown as mean (SD). BMI Body mass index