Skip to main content

Table 1 Patient demographics (n = 40)

From: Impact of gram negative bacteria airway recolonization on the occurrence of chronic lung allograft dysfunction after lung transplantation in a population of cystic fibrosis patients

  Total
n: 40
GNB recolonization
n: 28
GNB de-novo colonization
n: 7
Exempt of GNB
n: 5
p
Age, years 28.5 ± 10.46 28.6 ± 9.2 25.4 ± 8.9 34.2 ± 15 0.33
Sex, male 19 (47.5%) 14 (50%) 4 (57%) 1 (20%) 0.40
High emergency LTx 7 (17.5%) 6 (21.4%) 0 1 (20%) 0.40
Bilateral LTx 39 (97.5%) 28 (100%) 6 (85.7%) 5 (100%) 0.09
HLTx 1 (2.5%) 0 0 0 0.09
Lung ischemic time, minutes 355 ± 86.1 360 ± 99.5 351 ± 41.1 330 ± 33.2 0.77
CMV D+/R- 4 (10%) 2 (7.1%) 1 (14.3%) 1 (20%) 0.62
ICU length of stay, days 25.2 ± 33.2 30.8 ± 38 8.4 ± 5.2 17.2 ± 12 0.24
Length of invasive mechanical ventilation, days 17.5 ± 32.4 21.9 ± 38.3 3.7 ± 3.3 6.2 ± 5.5 0.36
Follow up, days 1413.5 ± 565.8 1509.3 ± 527.8 1044.3 ± 590.7 1394.2 ± 643.2 0.15
One year survival, % 100 100 100 100  
Best post-transplant FEV1, %predicted 83.8 ± 18 82.5 ± 19.3 90.8 ± 12.6 82.2 ± 16.7 0.59
CLAD 9 (22.5%) 3 (10.7%) 4 (57%)* 2 (40%) 0.02*
BOS 7 (17.5%) 3 (10.7%) 2 (28.6%) 2 (40%) 0.20
Time to BOS, months 36.4 (20.2) 27.3 (18.5) 25.5 (6.4) 61 (5.7) 0.09
RAS 2 (5%) 0 2 (28.6%)* 0 0.007*
Time to RAS, months 13 NA 13 NA  
  1. Definition of abbreviations: GNB Gram Negative Bacteria, LT Lung Transplant, HLT Heart Lung Transplant, ICU Intensive Care Unit, FEV1 Forced Expiratory Volume in 1 s, CLAD Chronic Lung Allograft Dysfunction, BOS Bronchiolitis Obliterans Syndrome, RAS Restrictive Allograft Syndrome. Data are expressed in n (%) and means±SDs