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Fig. 6 | BMC Microbiology

Fig. 6

From: Helicobacter pylori infection downregulates duodenal CFTR and SLC26A6 expressions through TGFβ signaling pathway

Fig. 6

Effect of TGFβ on forskolin- and PGE2-stimulated bicarbonate secretions in SCBN cells. SCBN cells were treated with TGFβ (5 ng/ml) for 24 h. The measurement of bicarbonate secretion in SCBN cells was performed as described in experimental procedures. a: Effect of TGFβ on forskolin-stimulated bicarbonate secretion in SCBN cells. Left panel is time course of change of forskolin-stimulated intracellular pH (pHi) in SCBN cells. Right panel is the comparison of ∆pHi. b: Effect of TGFβ on PGE2-stimulated bicarbonate secretion in SCBN cells. Left panel is time course of change of PGE2-stimulated intracellular pH (pHi) in SCBN cells. Right panel is the comparison of ∆pHi. Values are mean ± SE in each series. **P < 0.01 compared to controls

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