Lactic acid Bacteria isolated from European badgers (Meles meles) reduce the viability and survival of Bacillus Calmette-Guerin (BCG) vaccine and influence the immune response to BCG in a human macrophage model

Table 1 Total counts of microaerophilic bacteria and bacterial isolates displaying antimycobacterial activity from faecal samples of the 26 badgers selected for this study

Badgers:			Total Counts:			Isolates with antimycobacterial activity^f
IC^a	Sex^b	Weight (Kg)	MRS^c	PCA^d	MRS:PCA^e	Isolates with antimycobacterial activity^f
A	f	8.3	5.61	5.56	1.14	5, 6, 7, 8, 23, 37
B	m	10.1	5.98	5.93	1.12	4, 41, 53
C	f	8.2	6.36	6.38	0.96	34
D	m	10.2	7.54	7.61	0.85	4
E	f	7.5	5.72	5.71	1.02	12, 23, 24, 48
F	m	12.1	7.32	6.34	9.54	7, 20, 24, 44, 48
G	f	9.1	7.46	6.45	10.35	23, 24, 41, 42
H	f	8.8	6.70	6.40	2.00	33, 34
I	f	11.5	6.08	6.26	0.67	32, 47
J	f	10.7	5.38	5.40	0.96	2, 26
K	f	10.1	7.92	7.76	1.43	–
L	f	8.8	8.86	8.87	0.97	4
M	m	12.3	8.45	8.43	1.04	16, 17
N	m	8.4	8.95	8.08	0.75	43
O	f	8.0	8.76	8.87	0.78	44
P	m	10.8	8.38	8.53	0.71	5
Q	f	8.4	8.72	8.87	0.72	16
R	f	8.8	8.13	8.15	0.96	20
S	m	9.9	7.66	7.65	1.02	48
T	f	10	7.41	7.32	1.24	17
U	m	10.5	8.23	8.40	0.68	–
V	m	9	8.48	8.51	0.94	–
W	f	10	7.46	6.86	4.03	–
X	m	10	7.96	6.94	10.46	–
Y	m	12.4	7.08	6.56	3.33	–
Z	m	9.9	7.94	7.49	2.8	–
AA	m	9.1	7.93	6.92	10.24	–
AB	f	8.8	7.72	6.04	4.82	–

^aIdentification code
^bFemale (f) or Male (m)
^cTotal counts on MRS agar plates expressed as log₁₀
^dTotal counts on PCA plates expressed as log₁₀
^eTotal Counts ratio between MRS and PCA plates
^fIsolates from MRS that display antimicrobial activity against M. smegmatis on a stab-on-agar test. These isolates were named with the numbers indicated in the column and preceded with a letter from their corresponding animal IC

ISSN: 1471-2180